Ignite Creation Date:
2024-06-16 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06424899
Status:
RECRUITING
Last Update Posted:
2024-05-22
First Post:
2024-05-10
Brief Title:
A Study Comparing Neoadjuvant Chemoimmunotherapy and Immuno-consolidationafter Compared With Immunoconsolidation After Radical Chemoradiotherapy for Stage III Potentially Resectable NSCLC
Sponsor:
Zeng Jian
Organization:
Zhejiang Cancer Hospital
Study Overview
Official Title:
A Randomized Controlled Multicenter Phase II Clinical Study Comparing Neoadjuvant Chemoimmunotherapy and Immuno-consolidationafter Compared With Immunoconsolidation After Radical Chemoradiotherapy for Stage III Potentially Resectable NSCLC
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To evaluate the efficacy and safety adebrelimab in Combination with chemotherapy after 3 cycles as neoadjuvant therapy and surgery or chemoradiotherapy based on MDT compared with adebrelimab after chemoradiotherapy in potentially operable stage III NSCLC
Detailed Description:
In recent years tumor immunotherapy has become an important means of clinical treatment of tumor The emergence of immunotherapy has provided a new direction for the exploration of neoadjuvant therapy for non-small cell lung cancer The purpose of this study is to compare the use of adebrelimab in patients with stage III potentially resectable locally advanced NSCLC non-small cell lung cancer The study will directly compare the curative chemoradiotherapy plus immune maintenance therapy model Pacific model with the neoadjuvant immune therapy plus curative surgery plus immune maintenance therapy model Keynote-671 model This comparison aims to provide a basis for determining treatment plans for patients with locally advanced NSCLC
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None