Viewing Study NCT06429488



Ignite Creation Date: 2024-06-16 @ 11:48 AM
Last Modification Date: 2024-10-26 @ 3:30 PM
Study NCT ID: NCT06429488
Status: COMPLETED
Last Update Posted: 2024-05-31
First Post: 2024-05-17

Brief Title: Obsessive-compulsive Disorder Depression and Anxiety Among Patients With Crohns Disease
Sponsor: University of Jordan
Organization: University of Jordan

Study Overview

Official Title: Obsessive-compulsive Disorder Depression and Anxiety Among Patients With Crohns Disease
Status: COMPLETED
Status Verified Date: 2024-05
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Introduction Crohns disease CD and obsessive-compulsive disorder OCD are two distinct medical conditions that affect millions of people worldwide While numerous studies have explored anxiety and depression in CD there is a notable lack of research about the link between OCD and CD The aim of the study is to look for a relation between these seemingly unrelated conditions

Methods Patients with a diagnosis of Crohns disease were given four different questionnaires in order to assess for the presence of obsessive-compulsive disorder depression and anxiety symptoms using the OCI-R score DASS-21 PHQ-9 and GAD-7 The same questionnaires were used to assess healthy controls for similar symptoms
Detailed Description: This is an observational case-control study conducted at Jordan University Hospital Using hospital medical records patients with Crohns disease who had been treated and followed up at the gastro-enterology and colorectal clinics were contacted to obtain consent to participate in the research and to explain its goals and the nature of the questionnaires used Patients who agreed to participate were sent an online questionnaire to fill in Healthy Controls with no medical illness or mental illness were invited to fill in the same questionnaire The controls were relatives of patients attending the hospital for clinics not related to the gastrointestinal tract or psychiatry Patients and controls with documented psychiatric illnesses were excluded

The following psychological assessment tools were used

The Obsessive-Compulsive Inventory-Revised OCI-R for obsessive-compulsive symptoms It is composed of an 18-item self-report validated questionnaire that measures symptoms across 6 subscales including washing checking neutralizing obsessing ordering and hoarding The possible range of scores is 0-72

The Depression Anxiety Stress Scales-21 DASS-21 for overall emotional well-being It is a set of three self-report scales to understand the degree of stress and distress depressive and anxiety symptoms The shortened version was used which consists of 21 items and has been widely used for research and clinical purposes and is easy to administer

The Patient Health Questionnaire-9 PHQ-9 a nine-item depression scale of the patient health questionnaire to assess depressive symptoms The individual responses are interpreted as a score with depression divided from no depression to severe depression

The Generalized Anxiety Disorder-7 GAD-7 a seven-item tool used to measure or assess anxiety symptoms and the severity of generalized anxiety disorder GAD

Data analysis

The data was collected using Microsoft Forms and downloaded into Excel for coding and deidentification before being imported into the Statistical Package for Social Science IBM SPSS Statistics for Windows version 25 IBM Corp Armonk NY USA for analysis The chi-square test was used to compare different categorical variables The Mann-Whitney U test was used to compare non-categorical variables The Kruskal-Wallis test was applied to test for significant differences between the scales

Ethical consideration

This study adhered to the principles of the Declaration of Helsinki 1975 and was approved by the Institutional Review Board at Jordan University Hospital

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None