Ignite Creation Date:
2024-06-16 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06426771
Status:
RECRUITING
Last Update Posted:
2024-05-23
First Post:
2024-05-18
Brief Title:
Effect of Antimullerian Hormone Levels on the Inflammatory Index Phytochemical Index and NRF Nutrient Density
Sponsor:
Etlik Zubeyde Hanım Womens Health Care Training and Research Hospital
Organization:
Etlik Zubeyde Hanım Womens Health Care Training and Research Hospital
Study Overview
Official Title:
Investigation of Dietary Inflammatory Index Dietary Phytochemical Index and NRF Nutrient Density in Patients With High and Low Antimullerian Hormone Levels
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
AMH
Brief Summary:
The aim of the study was to calculate the dietary inflammatory index dietary phytochemical index and NRF nutrient density of the dietary pattern routinely consumed by women and to assess whether there is a difference between PCOS patients with high AMH levels and the group with low AMH levels
Detailed Description:
There is currently growing interest in the relationship between lifestyle reproductive health and fertility Recent research emphasizes the influence of environmental and lifestyle factors such as stress diet and nutritional status on reproductive health Ovarian reserve refers to the number and quality of eggs and is an indicator of reproductive potential Ovarian reserve is inversely proportional to the chronological age of the mother which is the most important determinant of reproductive capacity and reproductive success It has been shown that reproductive aging accelerates after the age of 35 Therefore the assessment of ovarian reserve is an important step in both the evaluation and treatment of infertility Markers of ovarian reserve include antral follicle count AFC which is determined by transvaginal ultrasound and serum levels of various biomarkers such as anti-Müllerian hormone AMH follicle-stimulating hormone FSH luteinizing hormone LH and estradiol Studies show that certain dietary patterns and the intake of certain nutrients are associated with endometriosis ovarian reserve and egg quality ovarian infertility and fertility In addition there is evidence that modifiable lifestyle factors such as adherence to certain dietary habits and avoidance of environmental toxins may also have positive effects on ovarian reserve Recent studies have shown that womens nutritional status body mass index and eating habits influence ovarian reserve
The Dietary Inflammatory Index DII is an index developed to assess the impact of general dietary habits on inflammation It is known that the dietary inflammatory index is high in chronic diseases associated with inflammation The Phytochemical Index is a calculation based on the consumption of fruits high in phytochemicals all vegetables except potatoes legumes whole grains and whole grain-containing foods and oilseeds that provides information about the level of phytochemicals in the diet The NRF Nutrient Density Index is a continuous function and represents an arithmetic combination of weighted variables In this continuous function algorithm the negative part foods that should be restricted is subtracted from the positive part foods that should be consumed In the calculation phase of this model foods were scored according to their nutrient content per 100 kcal and per serving size By calculating the nutrient density of the food consumed the quality of the persons diet can be determined
Based on this information it was planned to compare these 3 nutritional indices in patients diagnosed with PCOS with an AMH level above 332 ngml in the low ovarian reserve group without a PCOS diagnosis with an AMH level below 12 ngml and in normo-responder patients with an AMH level between these two values
The Dietary Inflammatory Index DII is an index developed to assess the impact of general dietary habits on inflammation It is known that the dietary inflammatory index is high in chronic diseases associated with inflammation The Phytochemical Index is a calculation based on the consumption of fruits high in phytochemicals all vegetables except potatoes legumes whole grains and whole grain-containing foods and oilseeds that provides information about the level of phytochemicals in the diet The NRF Nutrient Density Index is a continuous function and represents an arithmetic combination of weighted variables In this continuous function algorithm the negative part foods that should be restricted is subtracted from the positive part foods that should be consumed In the calculation phase of this model foods were scored according to their nutrient content per 100 kcal and per serving size By calculating the nutrient density of the food consumed the quality of the persons diet can be determined
Based on this information it was planned to compare these 3 nutritional indices in patients diagnosed with PCOS with an AMH level above 332 ngml in the low ovarian reserve group without a PCOS diagnosis with an AMH level below 12 ngml and in normo-responder patients with an AMH level between these two values
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None