Ignite Creation Date:
2024-06-16 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06422572
Status:
COMPLETED
Last Update Posted:
2024-05-21
First Post:
2024-05-07
Brief Title:
Tissue Kallikrein Protect Against Ischemic Stroke
Sponsor:
Qin Zhang
Organization:
Tongji Hospital
Study Overview
Official Title:
The Role of Tissue Kallikrein - Bradykinin System Targeting the Protection of Neurovascular Units in Ischemic Areas of Stroke
Status:
COMPLETED
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The results of previous studies were used to assess the causal association between TK levels and stroke occurrence at 5 and 12 years of follow-up respectively
Detailed Description:
Analyze the data of a 5-year follow-up on 2115 control individuals from the case-control study of the previous research We completed the 5-year follow-up on this group in 2016 whether they had a stroke whether they are alive and the cause of death
Conduct a 12-year follow-up on 6487 community individuals from the previous study whether they had a stroke within 12 years whether they are alive and the cause of death We collaborated with the hospital platforms computer center to conduct follow-up through AI questionnaire surveys followed by supplementing AI questionnaire data with telephone questionnaire surveys for those lost to follow-up
Utilize R language R Studio 411 for statistical analysis and plotting Evaluate the distribution of TK levels in the control group and its relationship with the 10-year predicted risk of stroke and the predictive role for stroke events within 5 years
Evaluate the distribution of TK levels in the community group and its relationship with the 10-year predicted risk of stroke and the predictive role for stroke events within 12 years
Conduct a 12-year follow-up on 6487 community individuals from the previous study whether they had a stroke within 12 years whether they are alive and the cause of death We collaborated with the hospital platforms computer center to conduct follow-up through AI questionnaire surveys followed by supplementing AI questionnaire data with telephone questionnaire surveys for those lost to follow-up
Utilize R language R Studio 411 for statistical analysis and plotting Evaluate the distribution of TK levels in the control group and its relationship with the 10-year predicted risk of stroke and the predictive role for stroke events within 5 years
Evaluate the distribution of TK levels in the community group and its relationship with the 10-year predicted risk of stroke and the predictive role for stroke events within 12 years
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None