Ignite Creation Date:
2024-06-16 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06424171
Status:
RECRUITING
Last Update Posted:
2024-05-22
First Post:
2024-02-26
Brief Title:
AFLETES-MRI A Cardiac and Cerebral Magnetic Resonance Imaging Study in Athletes With Atrial Fibrillation
Sponsor:
University of Leicester
Organization:
University of Leicester
Study Overview
Official Title:
Atrial Fibrillation and the Risk of Stroke in Veteran athLETES a Pilot Cardiac and Cerebral Magnetic Resonance Imaging Study - AFLETES-MRI
Status:
RECRUITING
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
AFLETES-MRI
Brief Summary:
Participation in exercise improves cardiovascular health However long-term endurance exercise may increase the risk of an irregular heart rhythm called atrial fibrillation AF
In AF blood flow is altered increasing the risk of clot formation in the heart which may enter the circulation and cause a stroke The risk of stroke can be reduced with the use of blood thinning medication Athletes with atrial fibrillation due to their healthy lifestyle are generally felt to be at low risk of stroke and many would not be offered blood thinning treatment using risk scores used in clinical practice
In a recent survey of almost one thousand athletes the investigators found that there was an increased risk of stroke in those with atrial fibrillation even in those without other risk factors for stroke
To further investigate these findings this study will use MRI scanning to look at the hearts and brains of athletes aged between 40-64 years old The researchers will assess athletes with and without atrial fibrillation as well as some athletes with atrial fibrillation who have had a stroke previously
The MRI scans will measure heart size and function as well as blood flow patterns in the heart The study will determine whether athletes with atrial fibrillation have evidence of stroke on brain MRI and whether these are related to abnormal flow patterns The results will help us decide whether a larger study should be performed
In AF blood flow is altered increasing the risk of clot formation in the heart which may enter the circulation and cause a stroke The risk of stroke can be reduced with the use of blood thinning medication Athletes with atrial fibrillation due to their healthy lifestyle are generally felt to be at low risk of stroke and many would not be offered blood thinning treatment using risk scores used in clinical practice
In a recent survey of almost one thousand athletes the investigators found that there was an increased risk of stroke in those with atrial fibrillation even in those without other risk factors for stroke
To further investigate these findings this study will use MRI scanning to look at the hearts and brains of athletes aged between 40-64 years old The researchers will assess athletes with and without atrial fibrillation as well as some athletes with atrial fibrillation who have had a stroke previously
The MRI scans will measure heart size and function as well as blood flow patterns in the heart The study will determine whether athletes with atrial fibrillation have evidence of stroke on brain MRI and whether these are related to abnormal flow patterns The results will help us decide whether a larger study should be performed
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None