Ignite Creation Date:
2024-06-16 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06432244
Status:
COMPLETED
Last Update Posted:
2024-05-29
First Post:
2024-05-22
Brief Title:
The Effect of the Number of Central Lymph Nodes on Changes in Parathyroid Function
Sponsor:
Shandong Provincial Hospital
Organization:
Shandong Provincial Hospital
Study Overview
Official Title:
The Effect of the Number of Central Lymph Nodes on Changes in Parathyroid Function
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study collected data from patients who underwent thyroidectomy in the Breast and Thyroid Surgery Department of Shandong Provincial Hospital from January 2020 to December 2023 by reviewing medical records The main calculation indicator was the changes in PTH before and after surgery This study grouped patients based on the number of central lymph nodes under postoperative paraffin pathology and statistically analyzed the changes and differences in PTH before and after surgery in different groups to verify the relationship between the number of central lymph nodes in the thyroid gland and parathyroid function and to provide reference for surgical selection in thyroid cancer patients with multiple cervical lymph node metastases
Detailed Description:
The central lymph nodes of the thyroid gland refer to the lymph nodes located around the thyroid and trachea The central lymph nodes are the primary site of thyroid cancer metastasis and therefore play an important role in thyroid surgery In thyroid surgery preventive central lymph node dissection is a routine procedure but during this process the parathyroid gland may be impaired due to surgical injury or insufficient blood supply
Hypothyroidism also known as parathyroidism is a common complication of thyroid surgery When the parathyroid gland is accidentally injured or its blood supply is disrupted it can lead to insufficient production of parathyroid hormone Parathyroid hormone is a key hormone that regulates blood calcium levels Insufficient levels can lead to hypocalcemia manifested as hand and foot spasms muscle spasms and even arrhythmia
From a surgical perspective the number of lymph nodes in the central region of the thyroid gland may affect the preservation and functional protection of the parathyroid gland A large number of lymph nodes indicates that they may have a wider range of disease invasion requiring more thorough lymph node dissection thereby increasing the risk of damaging the parathyroid gland or its blood supply
Hypothyroidism also known as parathyroidism is a common complication of thyroid surgery When the parathyroid gland is accidentally injured or its blood supply is disrupted it can lead to insufficient production of parathyroid hormone Parathyroid hormone is a key hormone that regulates blood calcium levels Insufficient levels can lead to hypocalcemia manifested as hand and foot spasms muscle spasms and even arrhythmia
From a surgical perspective the number of lymph nodes in the central region of the thyroid gland may affect the preservation and functional protection of the parathyroid gland A large number of lymph nodes indicates that they may have a wider range of disease invasion requiring more thorough lymph node dissection thereby increasing the risk of damaging the parathyroid gland or its blood supply
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None