Viewing Study NCT06434870



Ignite Creation Date: 2024-06-16 @ 11:48 AM
Last Modification Date: 2024-10-26 @ 3:30 PM
Study NCT ID: NCT06434870
Status: RECRUITING
Last Update Posted: 2024-05-30
First Post: 2024-05-22

Brief Title: Effect of Spinal Anesthesia in Elective Cesarean Cases on Frontal QRS Angle in Anemic and Non-Anemic Patients
Sponsor: Sanliurfa Mehmet Akif Inan Education and Research Hospital
Organization: Sanliurfa Mehmet Akif Inan Education and Research Hospital

Study Overview

Official Title: Comparison of the Effect of Spinal Anesthesia Applied in Elective Cesarean Cases on Frontal QRS Angle in Anemic and Non-Anemic Patients
Status: RECRUITING
Status Verified Date: 2024-05
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: The QRS-T angle represents a novel marker of myocardial repolarisation It is defined as the angle difference between the direction of ventricular depolarisation QRS wave and the direction of ventricular repolarisation T wave It is an indicator of instability in the electrophysiological properties of the myocardium and is associated with arrhythmias The frontal QRS-T angle is a straightforward cost-effective parameter that can be readily obtained from 12-lead electrocardiography

The most prevalent arrhythmias during pregnancy are atrial arrhythmias However ventricular tachyarrhythmias are exceedingly rare during pregnancy and may be life-threatening

Caesarean section is one of the most common surgical procedures General anaesthesia spinal anaesthesia and epidural anaesthesia can be employed in these patients Spinal anaesthesia is a frequently employed method in caesarean section operations due to its rapid onset of effect technical simplicity of application and higher probability of success

In pregnant women anaemia is defined as a haemoglobin concentration below 11 mgdL in the first trimester 11 mgdL in the second trimester and 105 mgdL in the third trimester
Detailed Description: The QRS-T angle represents a novel marker of myocardial repolarisation It is defined as the angle difference between the direction of ventricular depolarisation QRS wave and the direction of ventricular repolarisation T wave It is an indicator of instability in the electrophysiological properties of the myocardium and is associated with arrhythmias The frontal QRS-T angle is a straightforward cost-effective parameter that can be readily derived from 12-lead electrocardiography The angle between the QRS and T waves is a useful indicator of myocardial repolarisation It is associated with arrhythmias and instability in the electrophysiological properties of the myocardium The frontal QRS-T angle is a simple inexpensive parameter that can be easily obtained from 12-lead electrocardiography

Pregnancy has a profound effect on the cardiovascular system It results in an increase in blood volume heart rate venous pressure in the lower extremities and cardiac output Furthermore it can result in a reduction in peripheral resistance and pulmonary vascular resistance as well as a decline in blood pressure Furthermore it affects the cardiac conduction system rendering patients more susceptible to arrhythmias The most prevalent arrhythmias during pregnancy are atrial arrhythmias Ventricular tachyarrhythmias are relatively uncommon during pregnancy and can be life-threatening

One of the most common surgical procedures is caesarean section General anaesthesia spinal anaesthesia and epidural anaesthesia can be employed in these patients Spinal anaesthesia is a frequently employed method in caesarean section operations due to its rapid onset of effect technical ease of application and higher chance of success In addition to the beneficial effects direct cardiac and indirect cardiac side effects may be observed such as vasodilatation due to sympathetic denervation decreased right heart pressure and reflex bradycardia which depend on the level of block

In pregnant women haemoglobin values below 11 mgdL in the first trimester 11 mgdL in the second trimester and 105 mgdL in the third trimester are considered to indicate anaemia

The objective of this study was to investigate the effects of spinal anaesthesia in elective caesarean section cases on frontal QRS angle in anaemic and non-anaemic patients

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None