Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06430619
Status:
COMPLETED
Last Update Posted:
2024-05-28
First Post:
2024-05-09
Brief Title:
Can Novel Oxygenation Indices Guide the Diagnosis of Acute Respiratory Distress Syndrome
Sponsor:
Başakşehir Çam Sakura City Hospital
Organization:
Başakşehir Çam Sakura City Hospital
Study Overview
Official Title:
New Criteria for Classifying Acute Respiratory Distress Syndrome Severity Using a Machine Learning Approach Novel Oxygenation and Saturation Indices
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to determine the cut-off values of the new oxygenation indices and further investigate their capabilities in diagnosing ARDS and predicting its severity in ICU Additionally the investigators aim to compare these results with conventional oxygenation and saturation indices
Detailed Description:
Recent studies have shown that mechanical power MP values below 17 Jmin and driving pressure DP values below 15 cmH2O reduce intensive care unit ICU mortality Asar et al have introduced six new oxygenation indices utilizing MP and DP instead of Pmean OSI-MPtot OI-MPtot OSI-ΔPinsp OI-ΔPinsp OSI-MPdyn OI-MPdyn They compared the predictive abilities of these new indices for ICU mortality in Covid-ARDS C-ARDS patients with conventional oxygenation indices PF SpO2FiO2 OI OSI PaO2FiO2xPEEP and SpO2FiO2xPEEP OI-ΔPinsp OSI-ΔPinsp and OSI-MPdyn indices exhibited the highest predictive power for ICU mortality However cut-off values for the diagnosis and severity determination mild moderate and severe of ARDS patients have not been investigated
In this study our objective is to determine the cut-off values of the new oxygenation indices and further investigate their capabilities in diagnosing ARDS and predicting its severity in ICU Additionally the investigators aim to compare these results with conventional oxygenation and saturation indices
In this study our objective is to determine the cut-off values of the new oxygenation indices and further investigate their capabilities in diagnosing ARDS and predicting its severity in ICU Additionally the investigators aim to compare these results with conventional oxygenation and saturation indices
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None