Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06438874
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-03
First Post:
2024-05-23
Brief Title:
Type 2 Diabetes Post Exercise Arterial Stiffness
Sponsor:
University of Illinois at Chicago
Organization:
University of Illinois at Chicago
Study Overview
Official Title:
Type 2 Diabetes Post Exercise Arterial Stiffness
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The overall aim of this research proposal is to determine the impact of GLP1 agonists on post-exercise arterial stiffness Therefore the investigators will examine the cardiovascular responses to exercise in individuals with Type 2 Diabetes mellitus T2DM taking these medications during and following a graded maximal exercise test
Detailed Description:
Type 2 diabetes mellitus T2DM is a significant public health concern associated with increased cardiovascular morbidity and mortality Notably individuals with T2DM often exhibit increased arterial stiffness a key indicator of cardiovascular risk Pharmacological interventions such as GLP1 agonists have emerged as crucial treatments for T2DM offering glycemic control and potential cardiovascular benefits including improvements in blood pressure and arterial stiffness However while the effects of GLP1 agonists on glycemic control and blood pressure regulation have been explored their impact on arterial stiffness specifically in response to exercise remains largely unexplored in individuals with T2DM Arterial stiffness is a critical marker of cardiovascular health and its reduction is associated with decreased cardiovascular risk which include lowered blood pressure Therefore the overall aim of this research is to investigate whether GLP1 agonists attenuate arterial stiffness post exercise and reduce peak exercise blood pressure in individuals with T2DM
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None