Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06437873
Status:
COMPLETED
Last Update Posted:
2024-05-31
First Post:
2024-05-25
Brief Title:
Long-term Survival Outcomes of Total Thyroidectomy and Radioactive Iodine Therapy in Unilateral T3T4 FTC
Sponsor:
Dezhou Hospital Qilu Hospital of Shandong University
Organization:
Dezhou Hospital Qilu Hospital of Shandong University
Study Overview
Official Title:
Long-term Survival Outcomes of Total Thyroidectomy and Radioactive Iodine Therapy in Unilateral T3T4 Follicular Thyroid CarcinomaA Retrospective Propensity Score-Matched Study
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to thoroughly examine survival disparities in patients with T3 or T4 stage follicular thyroid carcinoma FTC as classified by the AJCC staging system It compares outcomes between those who underwent total thyroidectomy TT and those who did not and assesses the influence of radioactive iodine therapy RAIT on the survival of patients without TT Utilizing the SEER database a retrospective study identified patients diagnosed with T3 or T4 FTC categorizing them into two cohorts those treated with TT and those who were not No-TT The No-TT group was further analyzed to determine the impact of RAIT on patient survival Propensity score matching PSM was applied to adjust for confounding variables Survival analysis including Kaplan-Meier survival curves and Landmark analysis was conducted to evaluate the effects of surgical intervention and RAIT on overall survival OS and cancer-specific survival CSS
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None