Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06436950
Status:
RECRUITING
Last Update Posted:
2024-06-12
First Post:
2024-05-20
Brief Title:
Electrical Phrenic Nerve Stimulation in Patients With VIDD
Sponsor:
Peking University Third Hospital
Organization:
Peking University Third Hospital
Study Overview
Official Title:
Electrical Phrenic Nerve Stimulation in Patients With Ventilator-induced Diaphragm Dysfunction a Randomized Controlled Study
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to examine efficacy of transcutaneous electrical phrenic nerve stimulation TEPNS in ventilator-induced diaphragmatic dysfunction VIDD The investigators recruit VIDD patients and randomly assign the patients into TEPNS group and control group TEPNS group receives TEPNS twice a day for consecutive 5 days Control group only receives usual care The investigators collect diaphragm function indicators and outcomes to evaluate the efficacy
Detailed Description:
Ventilator-induced diaphragmatic dysfunction VIDD is common in intensive care unit ICU There is a need of measurements to improve VIDD The investigators hypothesize that transcutaneous electrical phrenic nerve stimulation TEPNS will increase diaphragmatic function This study is a single centre randomized controlled trial with control or treatment group in a 11 ratio Eligible patients include aged 18 years ventilated for at least 48 h with an expected stay of more than 7 days in the ICU and diaphragm thickening fraction DTF 25 The patients are randomly allocated to either receiveTEPNS and usual care TEPNS group or usual care only control group Blind is not used TEPNS is conducted twice a day for consecutive 5 days Electrodes are applied to bilateral neck skin which phrenic nerve runs underneath Clinical data are collected including baseline characteristics airway pressure esophageal pressure gastric pressure ventilation days ICU length of stay 28-day mortality etc
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None