Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06430918
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
2024-05-28
First Post:
2024-05-17
Brief Title:
Neuropathic Pain and its Relation to Sleep Quality in Knee Osteoarthritis
Sponsor:
Bozyaka Training and Research Hospital
Organization:
Bozyaka Training and Research Hospital
Study Overview
Official Title:
Coexistence of Night Pain and Neuropathic Pain in Patients With Knee Osteoarthritis
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary aim is to investigate the frequency and severity of neuropathic pain and its association with night pain in patients with knee osteoarthritis For this purpose a progressive longitudinal study design was planned The secondary aim is to investigate the relationship between night pain and neuropathic pain and sleep quality
Detailed Description:
Osteoarthritis OA is the most common form of arthritis in the world Classically OA presents with joint pain and loss of function however the disease is clinically very variable and can present merely as an asymptomatic incidental finding to a devastating and permanently disabling disorder
The severity of knee pain caused by osteoarthritis often does not correlate with the degree of degenerative changes in the joint In patients reporting night pain this may be related to inflammation but in the absence of clinical and laboratory findings of inflammation it is not possible to explain night pain only by the degree of joint damage The existence of a relationship between night pain and neuropathic pain may be a guide in looking for neuropathic pain in patients who have night pain and experience this pain severely and thus for planning an appropriate treatment for the patient
Patients with stage 2-4 knee OA will be evaluated in terms of demographic variables and outcome measurement parameters specified in the case report form The relationship between neuropathic pain scores and knee pain severity will be sought It will be studied whether there is a difference in outcome measurement parameters between those with neuropathic pain and those without Correlation analysis will be performed between sleep quality score and pain intensity scores The determinants of sleep quality will be evaluated by regression analysis
American College of Rheumatology criteria will be recruited Demographics and disease related variables will be recorded
The severity of knee pain caused by osteoarthritis often does not correlate with the degree of degenerative changes in the joint In patients reporting night pain this may be related to inflammation but in the absence of clinical and laboratory findings of inflammation it is not possible to explain night pain only by the degree of joint damage The existence of a relationship between night pain and neuropathic pain may be a guide in looking for neuropathic pain in patients who have night pain and experience this pain severely and thus for planning an appropriate treatment for the patient
Patients with stage 2-4 knee OA will be evaluated in terms of demographic variables and outcome measurement parameters specified in the case report form The relationship between neuropathic pain scores and knee pain severity will be sought It will be studied whether there is a difference in outcome measurement parameters between those with neuropathic pain and those without Correlation analysis will be performed between sleep quality score and pain intensity scores The determinants of sleep quality will be evaluated by regression analysis
American College of Rheumatology criteria will be recruited Demographics and disease related variables will be recorded
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None