Ignite Creation Date:
2024-06-16 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06430112
Status:
RECRUITING
Last Update Posted:
2024-05-28
First Post:
2024-05-21
Brief Title:
Liposomal Bupivacaine vs Ropivacaine for TAPBs
Sponsor:
Sun Yat-sen University
Organization:
Sun Yat-sen University
Study Overview
Official Title:
Liposomal Bupivacaine vs Ropivacaine for Ultrasound-guided Transversus Abdominis Plane Blocks in Laparoscopic Lower Abdominal Tumor Resection A Prospective Randomized Trial
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Few studies have compared the efficacy of ultrasound US-guided TAP blocks with Liposomal bupivacaineLB versus ropivacaine in reducing postoperative opioid usage in patients undergoing laparoscopic lower abdominal tumor Resection Therefore we are conducting this prospective randomized controlled trial to compare the postoperative analgesic effects of LB and ropivacaine for TAP blocks among patients undergoing laparoscopic colorectal procedures
Detailed Description:
This study aimed to investigate the impact of liposomal bupivacaine LB on postoperative opioid usage for ultrasoundUS-guided transversus abdominis plane TAP blocks in laparoscopic colorectal resections We divided 76 patients into two groups An injection of bilateral TAP blocks was administered to LB group using 133mg liposomal bupivacaine in each block 266mg total and to R group using 20 ml 025 ropivacaine in each block 40 ml total Opioid consumption and pain scores at 6h 24h 48h and 72h were recorded postoperatively as well as the total intraoperative remifentanil dose the hospital stay lengths after surgery and adverse events including dizziness nausea and vomiting
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None