Ignite Creation Date:
2024-06-16 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06446895
Status:
RECRUITING
Last Update Posted:
2024-06-06
First Post:
2024-05-27
Brief Title:
Biomarkers of Inflammation and Endothelial Dysfunction in Patients With Myocardial Infarction With Non-obstructive Coronary Arteries
Sponsor:
Hospital Universitario Getafe
Organization:
Hospital Universitario Getafe
Study Overview
Official Title:
Biomarkers of Inflammation and Endothelial Dysfunction in Patients With Myocardial Infarction With Non-obstructive Coronary Arteries
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
IMACORN-INFLI
Brief Summary:
Around 10 of patients with myocardial infarction MI present with nonobstructive coronary arteries MINOCA which pathophysiology is often uncertain The aim of the study is to evaluate inflammation and endothelial dysfunction biomarkers in MINOCA patients during both acute and stable phases comparing them with those with MI and obstructive coronary arteries MICAD
Detailed Description:
Prospective observational study in patients with Myocardial Infarction MI divided into two groups MI with obstructive coronary arteries MICAD and MI with non-obstructive coronary arteries MINOCA Levels of interleukin-6 tumor necrosis factor-alpha high-sensitivity C- reactive protein and asymmetric dimethylarginine will be determined at three time points within the 24 hours from the onset of pain discharge and two months after MI The association of biomarkers normalized by peak troponin value with the risk of MINOCA will be evaluated using logistic regression
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None