Ignite Creation Date:
2024-06-16 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06443333
Status:
RECRUITING
Last Update Posted:
2024-06-05
First Post:
2024-05-10
Brief Title:
National Multicentric Registry Study on Neuroimmunological Diseases in China
Sponsor:
Xuanwu Hospital Beijing
Organization:
Xuanwu Hospital Beijing
Study Overview
Official Title:
National Multicentric Registry Study on Neuroimmunological Diseases in China
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
NIDBase
Brief Summary:
The aim of this study is to establish a real-world clinical neuroimmune disease research cohort to follow up and observe the prognosis of patients with different subtypes and subgroups and to provide support for the treatment early warning and outcome prediction research of neuroimmune diseases
Detailed Description:
The purposes of this study are1Establishing a clinical neuroimmune disease research cohort2Collecting the blood cerebrospinal fluid and other biological samples of the enrolled patients to discover and detect the new neural antibodies so as to facilitate the diagnosis of related diseases3 Conducting in-depth exploration of the Genetic material of patients with neuroimmune diseases and healthy volunteers with second-generation sequencing technology discovering the pathogenic genes and the mechanism of disease progressionThe enrolled patients will be collected Clinical and therapeutic information Blood and cerebrospinal fluid from the patients will be collected for sequencing analysis and antibody detection They will also receive the 2-year follow-up with collection of basic clinical information cognitive function EDSS score etc Healthy volunteers will have their blood collected for sequencing analysis
Finish the gene sequencing analysis of blood samples from enrolled patients and healthy volunteers to establish the disease gene database and the reference gene database of the healthy population and find the unique expression quantitative trait loci eQTL in China so as to clarify the pathogenic genes and the key mechanism of neuroimmune disease occurrence and development
Finish the gene sequencing analysis of blood samples from enrolled patients and healthy volunteers to establish the disease gene database and the reference gene database of the healthy population and find the unique expression quantitative trait loci eQTL in China so as to clarify the pathogenic genes and the key mechanism of neuroimmune disease occurrence and development
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None