Ignite Creation Date:
2024-06-16 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06450080
Status:
RECRUITING
Last Update Posted:
2024-06-10
First Post:
2024-06-04
Brief Title:
Study of the Relationship Between Clinical Imaging and Biological Data in Patients With Squamous Cell Carcinoma of the Tongue
Sponsor:
Centre Hospitalier Universitaire Amiens
Organization:
Centre Hospitalier Universitaire Amiens
Study Overview
Official Title:
Study of the Relationship Between Clinical Imaging and Biological Data in Patients With Squamous Cell Carcinoma of the Tongue
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ClimaBio
Brief Summary:
Squamous cell carcinoma SCC could be a very aggressive cancer and has a bad prognosis if not detected early and thus is associated with high mortality The development of simple and reliable biomarkers for the early detection of SCC is one of the solutions to better diagnose treat these tumors evaluate and monitor treatments and hence reduce mortality In a previous work the investigators demonstrated the ability of Proton Magnetic resonance spectroscopy 1H-MRS to non-invasively assess spectroscopic and metabolic profiles of tongue tissue in healthy subjects In the present work the investigators challenge the use of in-vivo 1H-MRS as a potential method for non-invasive metabolic monitoring of patients with squamous cell carcinoma of the tongue undergoing therapy Thus the main objective is to study the spectroscopic and metabolic differences eg including variation in the metabolite TMA-Cho trimethylamine-choline of tongue tissue between healthy subjects and in patients with squamous cell carcinoma of the tongue before and after surgery
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None