Ignite Creation Date:
2024-06-16 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06453291
Status:
RECRUITING
Last Update Posted:
2024-06-11
First Post:
2024-06-07
Brief Title:
Assessment of Different Clinical Techniques to Treat Patients With Chronic Low Back Pain
Sponsor:
Iffat Anwar Medical Complex
Organization:
Iffat Anwar Medical Complex
Study Overview
Official Title:
Innovative Approaches in Managing Chronic Low Back Pain A Comparative Assessment of Clinical Techniques
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CLBP
Brief Summary:
This clinical trial aims to assess the effectiveness of different clinical techniques in treating patients with chronic low back pain CLBP Two test groups will be included one receiving conventional therapy NSAIDs and other physical therapy techniques and the other receiving a combination of neuromodulation and platelet-rich plasma PRP therapy Chronic pain persisting for more than three months inhibits natural pathways like GABA and promotes excitatory pathways leading to increased inflammation The study hypothesizes that neuromodulation via the dorsal root ganglion DRG and PRP therapy will provide superior pain relief and functional improvement compared to conventional therapy
Detailed Description:
Chronic low back pain CLBP affects millions of individuals worldwide significantly impacting quality of life and productivity Traditional treatments often involve NSAIDs and physical therapy but these methods sometimes fail to provide adequate relief Chronic pain is characterized by prolonged activation of the central and peripheral nervous systems resulting in sensitization and increased pain perception
The current study will evaluate two treatment modalities
1 Conventional Therapy This includes the use of nonsteroidal anti-inflammatory drugs NSAIDs and other standard physical therapy techniques
2 Neuromodulation PRP Therapy Neuromodulation is performed via the DRG to modulate excitatory pathways with medial sensory nerves being desensitized at 42C for 3-20 minutes PRP therapy involves the injection of concentrated platelets to promote healing and reduce inflammation
The study will provide valuable insights into the comparative effectiveness of these treatments potentially guiding future therapeutic strategies for CLBP
The current study will evaluate two treatment modalities
1 Conventional Therapy This includes the use of nonsteroidal anti-inflammatory drugs NSAIDs and other standard physical therapy techniques
2 Neuromodulation PRP Therapy Neuromodulation is performed via the DRG to modulate excitatory pathways with medial sensory nerves being desensitized at 42C for 3-20 minutes PRP therapy involves the injection of concentrated platelets to promote healing and reduce inflammation
The study will provide valuable insights into the comparative effectiveness of these treatments potentially guiding future therapeutic strategies for CLBP
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None