Ignite Creation Date:
2024-06-16 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06456814
Status:
RECRUITING
Last Update Posted:
2024-06-13
First Post:
2024-06-07
Brief Title:
Epidemiological Insights Into the Formation Progression and Rupture of Intracranial Aneurysms A Retrospective Multi-Center Hospital-Based Study in China
Sponsor:
Zhujiang Hospital
Organization:
Zhujiang Hospital
Study Overview
Official Title:
Epidemiological Insights Into the Formation Progression and Rupture of Aneurysms A Retrospective Multi-Center Hospital-Based Study in China
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a retrospective hospital-based and multi-center study aiming at investigating the potential exposures associated with the formation progression and rupture of intracranial aneurysms in Chinese population
Detailed Description:
A striking conflict exists between the fatal rupture of intracranial aneurysms IA and the passive approach to detecting IA through cerebrovascular examinations This is attributed to a limited understanding of risk factors for IA incidence and the resulting lack of cost-effective IA screening
This study aims to gain epidemiological insights into the exposures associated with the risk of IA incidence including formation progression and rupture in the Chinese population It integrates multi-modal data based on large-scale electronic medical records from high-volume stroke centers across China to investigate potential associations between various exposures and IA incidence
Patients with anonymous and unique IDs were screened for the presence of IA by formal readings from digital subtraction angiography DSA cranial computed tomography angiography CTA or magnetic resonance angiography MRA conducted by two radiologists which were then confirmed by two treating neurosurgeons using the raw images Using natural language processing in conjunction with medical records and multi-modal data patient exposures were extracted and assumed to be absent if no documentation was found across the databases
Through a series of retrospective analyses we aim to identify the exposures associated with IA incidence as much as possible to gather valuable insights for future prospective research
This study aims to gain epidemiological insights into the exposures associated with the risk of IA incidence including formation progression and rupture in the Chinese population It integrates multi-modal data based on large-scale electronic medical records from high-volume stroke centers across China to investigate potential associations between various exposures and IA incidence
Patients with anonymous and unique IDs were screened for the presence of IA by formal readings from digital subtraction angiography DSA cranial computed tomography angiography CTA or magnetic resonance angiography MRA conducted by two radiologists which were then confirmed by two treating neurosurgeons using the raw images Using natural language processing in conjunction with medical records and multi-modal data patient exposures were extracted and assumed to be absent if no documentation was found across the databases
Through a series of retrospective analyses we aim to identify the exposures associated with IA incidence as much as possible to gather valuable insights for future prospective research
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None