Ignite Creation Date:
2024-06-16 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06456229
Status:
RECRUITING
Last Update Posted:
2024-06-13
First Post:
2024-06-06
Brief Title:
Time to Return of Bowel Function Following Perioperative Probiotics in Colorectal Cancer Surgery
Sponsor:
National University Hospital Singapore
Organization:
National University Hospital Singapore
Study Overview
Official Title:
Time to Return of Bowel Function Following Perioperative Probiotics in Colorectal Cancer Surgery PICCS-1
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PICCS-1
Brief Summary:
There is pre-existing evidence that probiotics could be useful in the improvement of ileus rates One metaanalysis of 30 studies demonstrated a reduction in the prevalence of post-operative ileus as determined by time to flatus time to defecation as well as postoperative abdominal distension PMID37373843 More broadly in gastrointestinal surgery a meta-analysis of 21 randomised controlled trials similarly affirmed the speedier recovery of gastrointestinal function after surgery when probiotics were administered PMID 35231076 In spite of these advantages the routine use of probiotics perioperatively for colorectal cancer surgery is not performed in Singapore We therefore seek to perform a trial to investigate whether probiotic administration perioperatively may reduce post operative ileus rates
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None