Ignite Creation Date:
2024-06-16 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06454058
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
2024-06-12
First Post:
2024-06-06
Brief Title:
Association Between Euploid Embryo Grade and Maternal Age
Sponsor:
Inception Fertility LLC
Organization:
Inception Fertility LLC
Study Overview
Official Title:
Association Between Euploid Embryo Grade and Maternal Age a Retrospective Cross-sectional Study
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background Advanced maternal age AMA is associated with a reduction in live birth rate LBR after ART cycles The main reason for this reduction is the lower number of oocytes aspirated the number of developing embryos and the low number of euploid embryos available for transfer The impact of age on success rates after the transfer of an euploid embryo has been a matter of discussion with a recent meta-analysis showing a reduction in LBR after the transfer of an euploid blastocyst to women of AMA 1 There could be many reasons for this reduced LBR but they can be categorized into two broad categories - the uterus including the mothers health and the embryo including the oocyte and the sperm
It is possible that factors associated with reduced embryo quality would manifest in a lower embryo grade
It is possible that factors associated with reduced embryo quality would manifest in a lower embryo grade
Detailed Description:
Objective To study if there is an association between advanced maternal age and lower embryo grading of euploid embryos
Hypothesis Advanced maternal age is associated with a lower embryonic grade in euploid embryos
Study Design This is a retrospective cross-sectional study of euploid embryos from patients who have completed IVF with PGT-A testing at a fertility clinic in The Prelude Network US sites only A comparison of embryo grade between different age groups 35 40 will be done after controlling for baseline demographic characteristics
Hypothesis Advanced maternal age is associated with a lower embryonic grade in euploid embryos
Study Design This is a retrospective cross-sectional study of euploid embryos from patients who have completed IVF with PGT-A testing at a fertility clinic in The Prelude Network US sites only A comparison of embryo grade between different age groups 35 40 will be done after controlling for baseline demographic characteristics
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None