Ignite Creation Date:
2024-06-16 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06459713
Status:
COMPLETED
Last Update Posted:
2024-06-14
First Post:
2024-05-31
Brief Title:
Multiplex Respiratory PCR Results in Diabetic Pneumonia Cases
Sponsor:
Hisar Intercontinental Hospital
Organization:
Hisar Intercontinental Hospital
Study Overview
Official Title:
The Use of Multiplex Respiratory Polymerase Chain Reaction Test in Patient With Diabetes Mellitus Who Have a Newly Diagnosed of Community-acquired Pneumonia
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PCR
Brief Summary:
Multiplex respiratory polymerase chain reaction PCR test has gained wide acceptance as an alternative to conventional culture methods for the detection of the causative agent of community-acquired pneumonia CAP The aim of this study is to evaluate the positivity and to determine the causative agent of CAP using multiplex respiratory PCR test in patients with diabetes mellitus
Detailed Description:
A total of 151 adults diagnosed with CAP were enrolled Group 1 composed of patients who had diabetes n42 and group 2 consisted of patients who did not have diabetes n109 Demographic and clinical data of the subjects were collected and compared statistically
The multiplex respiratory PCR test positivity of group 1 was statistically higher than group 2 p0004 The most identified nasopharyngeal pathogen was SARSCoV2 in group 1 whereas in group 2 the most prevalent agent was Streptococcus pneumoniae p0002 p0628 Furthermore the amount of procalcitonin CRP neutrophil counts and the ratio of neutrophil-to-lymphocyte ratio NLR and CRP-to-lymphocyte CLR ratio on admission were statistically higher in group 1 than groups 2 p0012 p0002 p0001 p0001 p0001
Diabetic patients are at greater risk for developing CAP Therefore early detection and prompt treatment is crucial for diabetic patients with CAP to avoid morbidity and mortality Multiplex respiratory PCR test is an important method for identifying the causative agent of CAP rapidly
The multiplex respiratory PCR test positivity of group 1 was statistically higher than group 2 p0004 The most identified nasopharyngeal pathogen was SARSCoV2 in group 1 whereas in group 2 the most prevalent agent was Streptococcus pneumoniae p0002 p0628 Furthermore the amount of procalcitonin CRP neutrophil counts and the ratio of neutrophil-to-lymphocyte ratio NLR and CRP-to-lymphocyte CLR ratio on admission were statistically higher in group 1 than groups 2 p0012 p0002 p0001 p0001 p0001
Diabetic patients are at greater risk for developing CAP Therefore early detection and prompt treatment is crucial for diabetic patients with CAP to avoid morbidity and mortality Multiplex respiratory PCR test is an important method for identifying the causative agent of CAP rapidly
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None