Ignite Creation Date:
2024-07-17 @ 10:50 AM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06486155
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-07-03
First Post:
2024-06-26
Brief Title:
Evaluation of Axillary Lymph Node Metastasis Status of Breast Cancer Based on Pathological Images and Virtual Staining
Sponsor:
Yunnan Cancer Hospital
Organization:
Yunnan Cancer Hospital
Study Overview
Official Title:
Evaluation of Axillary Lymph Node Metastasis Status of Breast Cancer Based on Pathological Images and Virtual Staining
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to develop an artificial intelligence model to transform unstained lymph node tissue slice images directly into stained images The main questions it aims to answer are
Can the virtual staining model generate hematoxylin and eosin HE and immunohistochemistry IHC images suitable for clinical diagnosis from unstained paraffin-embedded lymph node slice images including those from breast axillary lymph nodes and other tumor lymph nodes
Can the virtual staining model generate HE and IHC images suitable for clinical diagnosis from unstained frozen sentinel lymph node slice images from breast cancer patients
Researchers will retrospectively collect paraffin-embedded lymph node slices from tumor patients and prospectively collect frozen sentinel lymph node slices from breast cancer patients
Can the virtual staining model generate hematoxylin and eosin HE and immunohistochemistry IHC images suitable for clinical diagnosis from unstained paraffin-embedded lymph node slice images including those from breast axillary lymph nodes and other tumor lymph nodes
Can the virtual staining model generate HE and IHC images suitable for clinical diagnosis from unstained frozen sentinel lymph node slice images from breast cancer patients
Researchers will retrospectively collect paraffin-embedded lymph node slices from tumor patients and prospectively collect frozen sentinel lymph node slices from breast cancer patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None