Ignite Creation Date:
2024-07-17 @ 10:56 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06468735
Status:
COMPLETED
Last Update Posted:
2024-06-21
First Post:
2024-06-19
Brief Title:
The Relationship Among Sarcopenia Preperitoneal Fat Thickness and Cholecystectomy
Sponsor:
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Organization:
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Study Overview
Official Title:
The Relationship Among Sarcopenia Preperitoneal Fat Thickness and Cholecystectomy The Good The Bad and The Ugly
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study was to examine the relationship between sarcopenia and visceral adiposity in participants with and without cholecystectomy
In this way the long-term effects of cholecystectomy operations which are commonly performed in the society and thought to be harmless will be evaluated
In this way the long-term effects of cholecystectomy operations which are commonly performed in the society and thought to be harmless will be evaluated
Detailed Description:
Cholecystectomy is recognized as a harmless operation with low mortality and morbidity and is commonly performed worldwide The unexplained increase in metabolic disorders such as dyslipidemia hyperglycemia non-alcoholic fatty liver disease NAFLD and sarcopenia with cholecystectomy in recent studies has led to the need for further investigation of these patients There are very few studies investigating the relationship among sarcopenia visceral adiposity and cholecystectomy In previous studies BIA or DEXA was used for sarcopenia assessment and non-US methods were used for visceral fat assessment In our study we aimed to determine the relationship among sarcopenia visceral adipose tissue and cholecystectomy by using US which is an easy cheap and a validreliable method
A total of 158 community-dwelling patients aged between 41 to 80 years including cholecystectomized N89 and non-cholecystectomized N69 participants from gastroenterology clinics were included
Sarcopenia assessment The quadriceps muscle thickness mm was divided by the BMI to get the sonographic thigh adjustment ratio STAR values Grip strength was assessed using an electronic hand dynamometer on the dominant hand side Three measurements were obtained from the dominant hand and the maximum value was taken for the analyses Participants in the chair stand test CST were instructed to rapidly rise and fall from a chair five times while keeping their arms folded across their chests The test was repeated three times and the mean time was recorded Together with low STAR values 10 for females and 14 for males having low grip strength 19 kg for females or 32 kg for males andor prolonged CST duration 12 seconds were used to diagnose sarcopenia
Intraabdominal visceral adipose tissue thickness was calculated by placing the probe 2-cm proximal to the midline of the umbilicus with minimal pressure and measuring the distance from the inner surface of the linea alba to the anterior wall of the abdominal aorta Subcutaneous maximum fat thickness was measured from the distance between the subcutaneous tissue and the linea alba from the same point Preperitoneal fat thickness was measured from the distal neighborhood of the xiphoid process 15 cm to the right side of the widest distance between the parietal peritoneum and the linea alba Minimum subcutaneous fat thickness was calculated as the distance measured from the distal neighborhood of the xiphoid process measured as the shortest distance between the outer part of the linea alba and the subcutaneous fat tissue
A total of 158 community-dwelling patients aged between 41 to 80 years including cholecystectomized N89 and non-cholecystectomized N69 participants from gastroenterology clinics were included
Sarcopenia assessment The quadriceps muscle thickness mm was divided by the BMI to get the sonographic thigh adjustment ratio STAR values Grip strength was assessed using an electronic hand dynamometer on the dominant hand side Three measurements were obtained from the dominant hand and the maximum value was taken for the analyses Participants in the chair stand test CST were instructed to rapidly rise and fall from a chair five times while keeping their arms folded across their chests The test was repeated three times and the mean time was recorded Together with low STAR values 10 for females and 14 for males having low grip strength 19 kg for females or 32 kg for males andor prolonged CST duration 12 seconds were used to diagnose sarcopenia
Intraabdominal visceral adipose tissue thickness was calculated by placing the probe 2-cm proximal to the midline of the umbilicus with minimal pressure and measuring the distance from the inner surface of the linea alba to the anterior wall of the abdominal aorta Subcutaneous maximum fat thickness was measured from the distance between the subcutaneous tissue and the linea alba from the same point Preperitoneal fat thickness was measured from the distal neighborhood of the xiphoid process 15 cm to the right side of the widest distance between the parietal peritoneum and the linea alba Minimum subcutaneous fat thickness was calculated as the distance measured from the distal neighborhood of the xiphoid process measured as the shortest distance between the outer part of the linea alba and the subcutaneous fat tissue
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None