Viewing Study NCT06476444



Ignite Creation Date: 2024-07-17 @ 11:04 AM
Last Modification Date: 2024-10-26 @ 3:33 PM
Study NCT ID: NCT06476444
Status: COMPLETED
Last Update Posted: 2024-07-01
First Post: 2024-06-21

Brief Title: Association of Sedentary Behaviour and Habitual Diet With Resting Fat Oxidation in Women With Overweight and Obesity
Sponsor: Hacettepe University
Organization: Hacettepe University

Study Overview

Official Title: Association of Physical Activity Sedentary Behaviour and Habitual Diet With Resting Fat Oxidation in Women With Overweight and Obesity
Status: COMPLETED
Status Verified Date: 2024-06
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: The aim of this study is to investigate the relationship between physical activity levels dietary patterns with fat oxidation at rest in normal lean individuals and those with overweight and obese
Detailed Description: Obesity is associated with a changing food environment where low-cost high-energy-dense fast foods are readily available and physical activity levels are decreasing Additionally metabolic flexibility defined as the organisms ability to switch between metabolic fuels is impaired in obesity and is known to play a significant role in the development of chronic diseases In these disease states a metabolically inflexible condition is typically characterized by a reduced ability to regulate fat oxidation during fasting and carbohydrate oxidation during satiety Therefore considering the rising trend in obesity understanding the factors related to metabolic flexibility becomes critical It is known that numerous factors such as diet composition eating habits physical activity level and sedentary behavior affect metabolic flexibility However unlike dietary and exercise interventions the number of studies examining the impact of individuals eating habits and physical activity levels on resting fat oxidation is limited and this topic has not yet been researched in obese individuals

Moreover another important concept known to have adverse effects on metabolic health independently of physical inactivity is sedentary behavior Sedentary behavior is defined as activities that require low energy expenditure while sitting reclining or lying down However the extent to which daily sedentary time and interruptions of this time with physical activities affect resting fat oxidation an important variable of metabolic health is not known

In this context the aim of this study is to comparatively determine the relationship between physical activity levels sedentary behaviors habitual diet and resting fat oxidation in normal-weight and overweightobese women A total of 118 healthy women aged 25-50 years normal weight n60 body mass index BMI 185 - 249 kgm² and overweightobese n60 BMI 250 - 349 kgm² will participate in this study All participants body composition and resting metabolic rate measurements will be conducted and fat and carbohydrate oxidation will be determined The dietary habits 4-day physical activity levels and sedentary behaviors of all participants will be assessed using appropriate measurement methods

The findings of this project are expected to reveal the extent to which dietary habits physical activity and sedentary behavior throughout the day affect resting fat oxidation in overweightobese and normal-weight individuals These findings will provide important evidence on how dietary habits and sedentary behaviors can improve resting fat oxidation an important indicator of metabolic flexibility without the need for dietary and exercise interventions

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None