Ignite Creation Date:
2024-07-17 @ 11:04 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06493500
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-07-10
First Post:
2024-06-30
Brief Title:
Efficacy of Formulated Eggshell Derived Nano-hydroxyapatite Containing Toothpaste With and Without Addition of Fluoride vs Conventional Desensitizing Fluoride Containing Toothpaste in Management of Dentin Hypersensitivity
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
Efficacy of Nano-hydroxyapatite Containing Tooth Paste on Dentin Hypersensitivity of Adult Patient
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
compare the effectiveness of Eggshell derived nano-Hydroxyapatite with and without fluoride and conventional fluoride containing tooth paste versus conventional desensitizing fluoride containing tooth paste on dentinal tubule occlusion and dentin mineral deposition
Detailed Description:
Recently advanced nanotechnology has taken a wide leap in improving the various measures in the treatment of hypersensitivity by its nanoparticles Nanoparticles can easily penetrate into dentin tubules which could act as mineralizing agents that block fluid movement within the dentin tubules when combined with various agents
Hydroxyapatite HAp is the major inorganic component of natural teeth and bone Nano-sized particles of hydroxyapatite are similar to the apatite crystals of tooth enamel in morphology and crystal structure and has been studied as a biomimetic material for the reconstruction of tooth enamel suffering from mineral loss because of its unique potential for remineralization Nano-hydroxyapatite n-HAp was considered a promising active ingredient used for the treatment of DH due to high biocompatibility and bioactivity In toothpastes HAp was included in the form of nanocrystals because they dissolve easier in this form Crystals of n-HAp included in dental products have a dimension of 50-1000 nm which enables them to act like fillers These products can penetrate and block the exposed dentinal tubules which are responsible for DH
Hydroxyapatite HAp is the major inorganic component of natural teeth and bone Nano-sized particles of hydroxyapatite are similar to the apatite crystals of tooth enamel in morphology and crystal structure and has been studied as a biomimetic material for the reconstruction of tooth enamel suffering from mineral loss because of its unique potential for remineralization Nano-hydroxyapatite n-HAp was considered a promising active ingredient used for the treatment of DH due to high biocompatibility and bioactivity In toothpastes HAp was included in the form of nanocrystals because they dissolve easier in this form Crystals of n-HAp included in dental products have a dimension of 50-1000 nm which enables them to act like fillers These products can penetrate and block the exposed dentinal tubules which are responsible for DH
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None