Ignite Creation Date:
2024-07-17 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06466629
Status:
RECRUITING
Last Update Posted:
2024-06-20
First Post:
2022-11-16
Brief Title:
The Optimal Timing of Vaccination in Pregnancy
Sponsor:
Elke Leuridan MD PhD
Organization:
Universiteit Antwerpen
Study Overview
Official Title:
The Optimal Timing of Vaccination in Pregnancy a Multi-dimensional Mechanistic Approach to Measure Immune Responses in Pregnant Women
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MATIMMUNE
Brief Summary:
The central aim of this study is to investigate the optimal timing of vaccination in pregnant women Therefore pregnant women will be vaccinated against pertussis at different timepoints and blood and breast milk samples will be taken at several timepoints The main objectives are to assess the impact of timing on humoral and cellular immune responses in pregnant women on antibody characteristics transferred across the placenta and on transplacental transport efficiency The impact of maternal pertussis vaccination and timing of maternal pertussis vaccination on breastmilk antibody composition will also be investigated as well as the impact of vaccination during pregnancy on the mucosal uptake of breastmilk IgA antibodies by the infant respiratory and gastrointestinal tract
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None