Ignite Creation Date:
2024-07-17 @ 11:26 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06494228
Status:
RECRUITING
Last Update Posted:
2024-07-10
First Post:
2024-07-02
Brief Title:
Comparison of Diagnostic Performances of 3D FLAIR DIR and PSIR Sequences in Optic Neuritis
Sponsor:
University Hospital Strasbourg France
Organization:
University Hospital Strasbourg France
Study Overview
Official Title:
Comparison of Diagnostic Performances of 3D FLAIR DIR and PSIR Sequences in Optic Neuritis
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Optic-Neuritis
Brief Summary:
Ultimately improve the care of patients suffering from multiple sclerosis 1st cause of acquired non-traumatic disability in adults and NMO spectrum diseases by using more efficient MRI sequences than the FLAIR sequence commonly used in detection of optic neuritis
In the literature many studies have already focused on comparing the sensitivity of detection of white matter demyelination plaques using FLAIR PSIR or DIR sequences
Some authors have shown better sensitivity of the PSIR sequence in the detection of demyelinating lesions of the marrow in multiple sclerosis compared to conventional sequences
Others have shown better performance of the combined use of PSIR and DIR sequences compared to the FLAIR sequence in the detection of cortical lesions in multiple sclerosis
However in the context of optic neuritis few comparative studies comparing these three sequences have been carried out
A 2022 study showed better diagnostic sensitivity of optic neuritis of the DIR sequence compared to the FLAIR sequence
A possible better diagnostic performance of a sequence not used in current practice in the detection of optic neuritis PSIR and DIR sequences would be possible to justify their use on a larger scale and ultimately improve patient care
In the literature many studies have already focused on comparing the sensitivity of detection of white matter demyelination plaques using FLAIR PSIR or DIR sequences
Some authors have shown better sensitivity of the PSIR sequence in the detection of demyelinating lesions of the marrow in multiple sclerosis compared to conventional sequences
Others have shown better performance of the combined use of PSIR and DIR sequences compared to the FLAIR sequence in the detection of cortical lesions in multiple sclerosis
However in the context of optic neuritis few comparative studies comparing these three sequences have been carried out
A 2022 study showed better diagnostic sensitivity of optic neuritis of the DIR sequence compared to the FLAIR sequence
A possible better diagnostic performance of a sequence not used in current practice in the detection of optic neuritis PSIR and DIR sequences would be possible to justify their use on a larger scale and ultimately improve patient care
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None