Ignite Creation Date:
2024-07-17 @ 11:29 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06488456
Status:
RECRUITING
Last Update Posted:
2024-07-08
First Post:
2024-06-28
Brief Title:
Psychometric Properties of the Therapy-Related Symptom Checklist-Children
Sponsor:
Ege University
Organization:
Ege University
Study Overview
Official Title:
Psychometric Properties of the Turkish Version of Therapy-Related Symptom Checklist for Children Scale
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Diagnosis and treatment of childhood cancers is an exhausting process that affects both children and their caring parents physically and mentally While the survival rate in childhood cancers was 28 in the 1960s this rate has increased up to 80 with the developments in treatment methods Although the main methods used in cancer treatment today are surgical treatment radiotherapy and immunotherapy the main component of cancer treatment is chemotherapy Improvements in chemotherapy protocols have increased survival however the use of high-dose chemotherapy may increase the frequency and severity of symptoms that may be seen in children Therefore diagnosis and management of treatment-related symptoms in the pediatric population receiving chemotherapy treatment as soon as possible is of vital importance as it will significantly affect the quality of life of children In this context this study aimed to add to the national literature by conducting a Turkish validity and reliability study of a checklist suitable for the use of health professionals in clinics for monitoring the side effects of chemotherapy In the study validity and reliability tests will be performed for intercultural scale adaptation
Detailed Description:
Leukaemias are the most common type of cancer in children and young people accounting for 13 of all cancers in the population Most childhood leukaemias are acute lymphocytic leukaemia ALL while the rest of the cases are acute myeloid leukaemia AML In childhood ALL peaks at the age of 2-4 years AML on the other hand can be seen throughout childhood and is more common in children under 2 years of age and in adolescents Chronic leukaemias are rarely seen in children
After the leukaemia is diagnosed and the type of leukaemia is determined the treatment protocol is decided according to the risk group of the disease The main treatment for childhood leukaemia is chemotherapy For children in the high-risk group high-dose chemotherapy may be given together with stem cell transplantation Treatment of leukaemias can last 2-3 years with maintenance treatment depending on the type and risk group Chemotherapy is known to cause many side effects in both adults and children The most well-known of these side effects are nausea and vomiting loss of appetite weight loss mucositis gastrointestinal system changes and fatigue alopecia pain depression
Monitoring and effective management of side effects of chemotherapy is one of the most important aspects of cancer treatment Symptoms resulting from the use of chemotherapies require careful monitoring to identify adverse side effects on patients During the diagnosis and treatment process of leukaemia children experience many symptoms at the same time When these symptoms are both related to each other and occur at the same time this is called a symptom cluster Studies emphasise that multiple symptoms are seen in children and adolescents with cancer When the literature was analysed it was seen that there were few studies involving the use of checklists to identify symptoms and symptom management the sample of which consisted of patients and their parents in Turkey However recognising symptom clusters may provide a better understanding of the structure of multiple symptoms and more effective symptom management In this context this study aimed to add to the national literature by conducting a Turkish validity and reliability study of a checklist suitable for the use of health professionals in clinics for monitoring the side effects of chemotherapy
After the leukaemia is diagnosed and the type of leukaemia is determined the treatment protocol is decided according to the risk group of the disease The main treatment for childhood leukaemia is chemotherapy For children in the high-risk group high-dose chemotherapy may be given together with stem cell transplantation Treatment of leukaemias can last 2-3 years with maintenance treatment depending on the type and risk group Chemotherapy is known to cause many side effects in both adults and children The most well-known of these side effects are nausea and vomiting loss of appetite weight loss mucositis gastrointestinal system changes and fatigue alopecia pain depression
Monitoring and effective management of side effects of chemotherapy is one of the most important aspects of cancer treatment Symptoms resulting from the use of chemotherapies require careful monitoring to identify adverse side effects on patients During the diagnosis and treatment process of leukaemia children experience many symptoms at the same time When these symptoms are both related to each other and occur at the same time this is called a symptom cluster Studies emphasise that multiple symptoms are seen in children and adolescents with cancer When the literature was analysed it was seen that there were few studies involving the use of checklists to identify symptoms and symptom management the sample of which consisted of patients and their parents in Turkey However recognising symptom clusters may provide a better understanding of the structure of multiple symptoms and more effective symptom management In this context this study aimed to add to the national literature by conducting a Turkish validity and reliability study of a checklist suitable for the use of health professionals in clinics for monitoring the side effects of chemotherapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None