Ignite Creation Date:
2024-07-17 @ 11:35 AM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06477562
Status:
COMPLETED
Last Update Posted:
2024-06-27
First Post:
2024-06-21
Brief Title:
Surveillance Endoscopy After Proximal Gastriectomy With Double Tract Reconstruction
Sponsor:
Saint Vincents Hospital Korea
Organization:
Saint Vincents Hospital Korea
Study Overview
Official Title:
The Success Rate and Associated Factors for Surveillance Endoscopy After Proximal Gastrectomy With Double Tract Reconstruction Multicenter Retrospective Study
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary purpose of surveillance endoscopy after gastric cancer surgery is to detect malignancy recurrence in the remnant stomach This study aims to analyze the rate of proper remnant stomach observation following proximal gastrectomyPG with double tract reconstruction DTR Data from patients who underwent PG with DTR for gastric cancer at six institutions in South Korea from 2011 to 2023 were included Clinicopathological and serial endoscopic data were retrospectively reviewed and analyzed Successful surveillance endoscopy was defined as obtaining an endoscopic image of the pyloric antrum Factors associated with successful endoscopy were analyzed using a mixed-effects logistic regression model A total of 634 surveillance endoscopies were performed on 160 patients after PG with DTR The median duration from surgery to the endoscopy was 175 months range 0-137 months The success rate of the endoscopies was 756 with a mean time of 27173005 seconds to reach the pyloric antrum The average total procedure time for successful endoscopic examinations was 43943360 seconds compared to 37373260 seconds for failed examinations p0033 Among patients who underwent the procedure twice or more 65 had all endoscopic examinations fail while 28 of those who underwent the procedure three times or more experienced failure in all examinations Factors associated with successful endoscopy included longer procedure time OR 132 95 CI 101-172 endoscopy performed by a non-surgeon OR 019 95 CI 011-036 longer duration after surgery OR 133 95 CI 102-172 and younger age OR 070 95 CI 049-097 Understanding the anatomic alterations after PG with DTR is crucial for the success of surveillance endoscopy Additionally the duration from surgery to endoscopy is associated with the success of the examination and the rate of failure across all serial endoscopies is very low Therefore clinicians should perform endoscopies with sufficient procedure time and conduct endoscopies regardless of the failure of previous examinations
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None