Ignite Creation Date:
2024-07-17 @ 11:47 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06470737
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-24
First Post:
2024-06-14
Brief Title:
Investigation of Corticospinal Excitability Aspects of Itch and Pain
Sponsor:
Aalborg University
Organization:
Aalborg University
Study Overview
Official Title:
Investigation of the Neurophysiological and Psychological Aspects of Itch
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The experiment consists of three experimental sessions conducted over a period of two weeks In the first experimental session we apply in your hand either an injection of salt water 7 NaCl or we apply small needles from the plant mucuna pruriens or histamine 1 For 10 minutes after this you are to assess the itch and pain you perceive We will also apply non-invasive magnetic stimulations to your brain During the experiment you should fill in questionnaires The second and third experimental sessions are conducted in the same way as the first session
The purpose of this experiment is to investigate the changes appearing in the brain during artificially applied itch and pain corticomotor adaptations
The purpose of this experiment is to investigate the changes appearing in the brain during artificially applied itch and pain corticomotor adaptations
Detailed Description:
The experiment consists of three experimental sessions conducted over a period of two weeks The duration of each session is approx two hours In the first experimental session we apply one of three experimental methods in your hand either an injection of salt water 7 NaCl or we apply small needles from the plant mucuna pruriens or histamine 1 Histamine is an itch-provoking substance formed in the human body For 10 minutes after this you are to assess the itch and pain you perceive on a scale from 0 to 10 in which 0 is no itchpain and 10 is worst itchpain imaginable We will also apply non-invasive magnetic stimulations to your brain This is done using a magnetic coil which is held over your head During the experiment you should fill in questionnaires about how you experience itchpain and about your personality The second and third experimental sessions are conducted in the same way as the first session However we will apply one of the other two experimental methods than the one used in the first session ie first session histamine second session plant needles third session injection with salt water The experimental methods will be applied in random order
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None