Ignite Creation Date:
2024-07-17 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06493695
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-07-10
First Post:
2024-06-23
Brief Title:
CES and EGChatbot in Reducing Anxiety Depression Insomnia and Mental Risk
Sponsor:
China Medical University Hospital
Organization:
China Medical University Hospital
Study Overview
Official Title:
Cranial Electrical Stimulation and Exercise Group Chatbot
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The objective of this three-year study is to provide comprehensive care to young adults presenting with ARMS The aim is use an exercise group EGChat developed by prior study and CES to decrease cognitive mental risks improve emotional stability enhance sleep quality and elevate overall life satisfaction A randomized controlled trial RCT design will be conducted using purposive sampling to recruit 180 young adults with ARMS from a medical center and its affiliated hospitals Participants will be randomly assigned to one of three groups undergoing a 16-week intervention EGChat plus CES EGChat without CES or CES without EGChat groups The study integrates the EGChat application into an online health promotion platform coupled with CES intervention to enhance the biological and psychological health of individuals at ARMS The goal of this RCT study is to enhance the biological and psychological well-being of individuals with ARMS covering exercise levels Brain-Derived Neurotrophic Factor BDNF levels health-promoting behaviors metabolic indexes cognitive mental risks emotional status sleep quality and overall life quality Assessments will occur at baseline T0 8 weeks into the intervention T1 upon completion of the 16-week intervention T2 and during a follow-up assessment at 3 months post-intervention T3 The study will utilize generalized estimating equations GEE for mixed model repeated measures analysis to evaluate the significant influences of the intervention and interactions between study variables utilizing group-time interaction
Detailed Description:
In our previous study the two-year psychosis transition rate was 833 comparatively lower than rates reported in other international studies Our findings highlight that individuals in the at-risk mental state ARMS category face cognitive emotional and sleep-related challenges leading to compromised self-identity and impairments in daily functioning A significant proportion of young adults at risk of mental health issues not only display cognitive vulnerabilities but also endure emotional instability and sleep disturbances increasing the likelihood of suicidal ideation and persistent self-harming behaviors Its clear that individuals facing mental health challenges especially those with ARMS require support from the health system Exercise has been linked to enhanced cognitive function and mental health The mental health chatbot as a promising tool for adolescents and young adults in the ARMS showing potential in alleviating anxiety depression and mental health risks Additionally cranial electrotherapy stimulation CES is recommended as a safe and effective approach to address sleep-related problems Together these interventions may be proposed as a comprehensive care strategy providing secure support for individuals with ARMS
The objective of this three-year study is to provide comprehensive care to young adults presenting with ARMS The aim is use an exercise group EGChat developed by prior study and CES to decrease cognitive mental risks improve emotional stability enhance sleep quality and elevate overall life satisfaction A randomized controlled trial RCT design will be conducted using purposive sampling to recruit 180 young adults with ARMS from a medical center and its affiliated hospitals Participants will be randomly assigned to one of three groups undergoing a 16-week intervention EGChat plus CES EGChat without CES or CES without EGChat groups The study integrates the EGChat application into an online health promotion platform coupled with CES intervention to enhance the biological and psychological health of individuals at ARMS The goal of this RCT study is to enhance the biological and psychological well-being of individuals with ARMS covering exercise levels Brain-Derived Neurotrophic Factor BDNF levels health-promoting behaviors metabolic indexes cognitive mental risks emotional status sleep quality and overall life quality Assessments will occur at baseline T0 8 weeks into the intervention T1 upon completion of the 16-week intervention T2 and during a follow-up assessment at 3 months post-intervention T3 The study will utilize generalized estimating equations GEE for mixed model repeated measures analysis to evaluate the significant influences of the intervention and interactions between study variables utilizing group-time interaction Additionally a machine-learning framework for EGChat will be implemented to enhance outcome predictions The analysis of these machine-learning algorithms will be conducted using the WEKA software
Comprehensive care intervention programs for individuals with ARMS should address the management of cognitive mental risks anxiety depression and insomnia The study findings provide evidence supporting the effectiveness of EGChat and CES in assisting young adults with ARMS The ultimate goals are to achieve early intervention delay the onset of psychosis impede disease progression and enhance the patients capacity for self-management and societal adaptation
The objective of this three-year study is to provide comprehensive care to young adults presenting with ARMS The aim is use an exercise group EGChat developed by prior study and CES to decrease cognitive mental risks improve emotional stability enhance sleep quality and elevate overall life satisfaction A randomized controlled trial RCT design will be conducted using purposive sampling to recruit 180 young adults with ARMS from a medical center and its affiliated hospitals Participants will be randomly assigned to one of three groups undergoing a 16-week intervention EGChat plus CES EGChat without CES or CES without EGChat groups The study integrates the EGChat application into an online health promotion platform coupled with CES intervention to enhance the biological and psychological health of individuals at ARMS The goal of this RCT study is to enhance the biological and psychological well-being of individuals with ARMS covering exercise levels Brain-Derived Neurotrophic Factor BDNF levels health-promoting behaviors metabolic indexes cognitive mental risks emotional status sleep quality and overall life quality Assessments will occur at baseline T0 8 weeks into the intervention T1 upon completion of the 16-week intervention T2 and during a follow-up assessment at 3 months post-intervention T3 The study will utilize generalized estimating equations GEE for mixed model repeated measures analysis to evaluate the significant influences of the intervention and interactions between study variables utilizing group-time interaction Additionally a machine-learning framework for EGChat will be implemented to enhance outcome predictions The analysis of these machine-learning algorithms will be conducted using the WEKA software
Comprehensive care intervention programs for individuals with ARMS should address the management of cognitive mental risks anxiety depression and insomnia The study findings provide evidence supporting the effectiveness of EGChat and CES in assisting young adults with ARMS The ultimate goals are to achieve early intervention delay the onset of psychosis impede disease progression and enhance the patients capacity for self-management and societal adaptation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None