Viewing Study NCT06465979



Ignite Creation Date: 2024-07-17 @ 12:00 PM
Last Modification Date: 2024-10-26 @ 3:32 PM
Study NCT ID: NCT06465979
Status: RECRUITING
Last Update Posted: 2024-06-20
First Post: 2024-06-13

Brief Title: Perception of Speech in Context by Listeners With Healthy and Impaired Hearing
Sponsor: University of Louisville
Organization: University of Louisville

Study Overview

Official Title: Perception of Speech in Context by Listeners With Healthy and Impaired Hearing
Status: RECRUITING
Status Verified Date: 2024-06
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Recognition of speech sounds is accomplished through the use of adjacent sounds in time in what is termed acoustic context The frequency and temporal properties of these contextual sounds play a large role in recognition of human speech Historically most research on both speech perception and sound perception in general examine sounds out-of-context or presented individually Further these studies have been conducted independently of each other with little connection across labs across sounds etc These approaches slow the progress in understanding how listeners with hearing difficulties use context to recognize speech and how their hearing aids andor cochlear implants might be modified to improve their perception This research has three main goals First the investigators predict that performance in speech sound recognition experiments will be related when testing the same speech frequencies or the same moments in time but that performance will not be related in further comparisons across speech frequencies or at different moments in time Second the investigators predict that adding background noise will make this contextual speech perception more difficult and that these difficulties will be more severe for listeners with hearing loss Third the investigators predict that cochlear implant users will also use surrounding sounds in their speech recognition but with key differences than healthy-hearing listeners owing to the sound processing done by their implants In tandem with these goals the investigators will use computer models to simulate how neurons respond to speech sounds individually and when surrounded by other sounds
Detailed Description: Participants in this study listen to speech played at a comfortable volume and respond by indicating what they heard either in open-ended form or by choosing among a set of options displayed on a computer They are seated inside a sound booth and complete the task at their own pace with little intervention needed from the experimenter Upon arrival at the lab participants are given a brief description of the topic of the research how earlier sounds influence our perception of later speech sounds and are presented with a detailed informed consent form Their demographic information is collected and then the experiment is demonstrated Breaks are offered between testing blocks which last about 10-15 minutes each

The main differences in the protocol consist of the various stimulus manipulations which are designed to specifically control aspect of the voice that the participant hears For example the sound can be manipulated to emphasize higher or lower frequencies or be spoken relatively slowly or quickly or manipulated to sound degraded as if the participant has a hearing loss In all occasions the manipulations are signaled to the participant The outcome measure typically consists of the pattern of word identification and specifically how that pattern changes depending on acoustic properties of the sounds heard before the target word

Additional comparison measurements are taken of the participants ability to hear and repeat words or sentences in background noise

Once an experiment is ready to launch participants are randomly assigned to different testing conditions interventions But in most of the planned experiments participants complete identical protocols except that the specific ordering of many speech stimuli is randomized within the testing session After the participant completes all of the testing blocks they are debriefed about the full nature of the study the hypotheses and the larger scope of the project in the context of speech communication

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None
Secondary IDs
Secondary ID Type Domain Link
R01DC020303 NIH None None