Ignite Creation Date:
2024-07-17 @ 12:05 PM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06487663
Status:
RECRUITING
Last Update Posted:
2024-07-05
First Post:
2024-06-09
Brief Title:
TACE Combined With Immune Checkpoint Inhibitors for Liver Malignant Tumors
Sponsor:
Tianjin Medical University Cancer Institute and Hospital
Organization:
Tianjin Medical University Cancer Institute and Hospital
Study Overview
Official Title:
Transcatheter Hepatic Artery Chemoembolization Combined With Immune Checkpoint Inhibitors for Liver Tumors
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TIKET
Brief Summary:
This study will evaluate the efficacy and safety of TACE combined with immune checkpoint inhibitors to treat unresectable hepatocellular carcinoma
Detailed Description:
The specific operation of TACE is based on the CSCO Diagnosis and Treatment Guidelines for Primary Liver Cancer 2022 Edition TACE is performed through microcatheters After TACE the coaxial catheter is retained in the hepatic artery or left or right hepatic artery branch The specific body plan is oxaliplatincalcium folinate5-Fu FOLFOX J Hepatol 2018 Oxaliplatin 85mgm2 was continuously injected through arterial pump for more than 4 hours on the first day After HAIC is completed remove the catheter and sheath Repeat catheterization in the next treatment cycle
Immune checkpoint inhibitors can be administered arterial starting after the first TACE treatment q4w 3 days If the situation requires the arterial administration of ICI can be adjusted forward or backward for 7 days to adapt to TACE treatment
Immune checkpoint inhibitors can be administered arterial starting after the first TACE treatment q4w 3 days If the situation requires the arterial administration of ICI can be adjusted forward or backward for 7 days to adapt to TACE treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None