Ignite Creation Date:
2024-10-25 @ 7:48 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06547749
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-02
Brief Title:
Vitamin D Supplementation in Critically Ill Children With Respiratory Disease
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Vitamin D Supplementation in Critically Ill Children With Respiratory Disease
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To evaluate the role of vitamin D supplementation in critically ill children with respiratory disease regarding their outcome
Detailed Description:
Vitamin D is involved in the process of immunomodulation especially in the context of autoimmunity Vitamin D has multiple pharmacological effects such as alleviating the inflammatory response promoting phagocytosis and inducing lymphocyte proliferation previous studies have demonstrated that patients with lower serum vitamin D levels had a longer length of hospital stay and might have an independent relationship with the duration of mechanical ventilation MV in critically ill children
Approved Vitamin D Supplementation Regimens
The recommended daily allowance RDA or adequate intake AI suggested by the Institute of Medicine IOM and supported by Health Canada are 400 IU for infants and 600 IU for older children
Approved High-Dose Regimens
In addition to RDA the IOM provides a higher age-specific dose called the tolerable upper intake level UL which ranges from 1000 to 4000 IU
Approved Vitamin D Supplementation Regimens
The recommended daily allowance RDA or adequate intake AI suggested by the Institute of Medicine IOM and supported by Health Canada are 400 IU for infants and 600 IU for older children
Approved High-Dose Regimens
In addition to RDA the IOM provides a higher age-specific dose called the tolerable upper intake level UL which ranges from 1000 to 4000 IU
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None