Ignite Creation Date:
2024-10-25 @ 7:51 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06579898
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-03-07
Brief Title:
The Effect of Progressive Resistance Exercise Training PRET on CVRF in Adults With ID
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effect of Progressive Resistance Exercise Training PRET on Cardiovascular Risk Factors in Adults With ID
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PRET
Brief Summary:
Thanks to improved healthcare the life expectancy of people with ID is increasing and is approaching that of the general population Several studies have shown that most cardiovascular disease CVRF risk factors are as common or even more common in people with ID than in the general population The guidelines of the American College of Sport Medicine ACSM state that a resistance training RT programme can can effectively reduce CVRF if performed at a high intensity A secondary benefit of RT is the increase in muscle strength and muscle mass that can reduce and can improve the ability to perform activities of daily living ADL also two common problems in people with ID
Detailed Description:
This study has a repeated time series design with one study group The study period will last one year and is divided into a 12-week baseline period a 24-week intervention period PRET programme and a 12-week follow-up period The PRET programme will take 24 weeks and consists of two sessions per week with at least 48 hours between the sessions The intervention will be led by experienced physiotherapists and physical activity instructors employed by the care providers All instructors take part in a training prior to the study In this training the intervention protocol and exercises will be discussed and practiced ensuring that the intervention is delivered according to the protocol Every session consists of seven exercises RESID to train all large muscle groups The programme is in accordance with the ACSM guidelines and characterised by four mesocycles Each mesocycle consists of six weeks of training After each mesocycle the training intensity will increase gradually and within each mesocycle the weights will be adjusted in a way that the intensity remains equal Training intensity will be measured by the percentage of the heaviest load one can lift for one repetition of 1RM In the first mesocycle participants are introduced to the resistance exercises and familiarised to the training protocol They will learn to perform the exercises safely and with good posture During mesocycles 2 3 and 4 the number of repetitions will be gradually decreased while the training intensity will be gradually increased until vigorous intensity is reached in the fourth mesocycle 80 of 1RM The resting time between sets will depend on the training intensity and varies between 30 seconds and 2 minutes The instructors will register attendance training intensity performed number of sets and repetitions and the weights used for each exercise in a log
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None