Ignite Creation Date:
2024-10-25 @ 7:55 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06596954
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-11
Brief Title:
Lymphocyte-sparing Thoracic Radiotherapy for Esophageal Squamous Cell Carcinoma
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Lymphocyte-sparing Thoracic Radiotherapy Vs Conventional Radiotherapy for Esophageal Squamous Cell Carcinoma Treated with Neoadjuvant Therapy an Open Label Randomized Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Esophageal squamous cell carcinoma ESCC is one of the most aggressive malignant tumors Although neoadjuvant chemoradiotherapy combined with surgery has significantly improved the survival rate of patients with locally advanced esophageal cancer approximately half of the patients will experience local regional recurrence or distant metastasis Lymphocytes are crucial immune cells in the human body playing a key role in combating infections and tumor development In recent years an increasing body of research has indicated that lymphocyte depletion is a significant factor associated with poor prognosis in various solid tumors including esophageal cancer The lymphocyte depletion caused by radiotherapy has garnered considerable attention from oncologists However there is still a lack of prospective clinical research data on lymphocyte protection in thoracic tumors Therefore this study aims to provide high-level evidence from evidence-based medicine regarding the correlation between lymphocyte depletion and prognosis in esophageal cancer patients offering more effective strategies and methods to improve the outcomes of neoadjuvant chemoradiotherapy for esophageal cancer
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None