Viewing Study NCT06515561



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Study NCT ID: NCT06515561
Status: NOT_YET_RECRUITING
Last Update Posted: None
First Post: 2024-07-17

Brief Title: Prevalence of Teeth Discoloration Associated Risk Factors and the Most Common Shade Among Group of Egyptian Population
Sponsor: None
Organization: None

Study Overview

Official Title: Prevalence of Teeth Discoloration and Associated Risk Factors and Determination of the Most Common Shade Among Group of Egyptian Population Educational Hospital Based Cross Sectional Study
Status: NOT_YET_RECRUITING
Status Verified Date: 2024-07
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: The aim of this study is to assess the prevalence of tooth discoloration and explore its associated risk factors including local cultural practices or environmental conditions among a group of adults aged 20 to 45 years in an Egyptian population sample Moreover we aim to identify the most common dental shades in the same sample
Detailed Description: Discoloration of teeth is a frequent dental finding and it is often esthetically displeasing and psychologically traumatizing to the patient Manuel et al 2010 Changes in the three distinct layers of the tooth enamel dentin and cementum are known to cause modification in the appearance of the teeth leading to a change in its light transmission and reflection properties Watts et al 2001 Generally tooth discoloration is said to have occurred when there is a deviation in tooth color Suresh and Gopi in 2010 noted that the normal color of primary teeth is bluish white whereas the color of permanent teeth is grayish white or yellowish white The teeth of adults usually appear more yellow or grayish yellow than those of younger persons because as one ages the enamel becomes thinner from physiological wear while the dentin becomes thicker from the deposition of secondary dentin There are two types of tooth discoloration extrinsic and intrinsic while the extrinsic type is apparent on the outer surface of the teeth the intrinsic type stains are coming from inside of the teeth The main cause of intrinsic tooth discoloration is the decomposition of pulp tissue which is the first indication of pulp death Suresh Gopi 2010 Other causes of intrinsic tooth discoloration are enamel opacities dental caries tetracycline minocycline and doxycycline staining and enamel hypoplasia Koleoso et al 2004 These medications can leave a characteristic bright-yellow band that fluoresces under ultraviolet light tetracycline or a green-gray or blue-gray intrinsic staining minocycline Also Fluoride can cause enamel discoloration through hypomineralization when too much of it is ingested during the early maturation stage of enamel formation In addition dental materials used for dental restorations like amalgam restorations can generate corrosion products such as silver sulfide which can leave a gray-black color on the teeth

On the other hand extrinsic dental discoloration might be due to tea coffee tobacco smokingchewing betel nut chewing drugs eg chlorhexidine mouth rinse iron salts heavy metals eg silver nitrate and lead essential oils amoxicillin-clavulinic acid ciprofloxacin linezolide and glibenclamide Kumar et al 2012 Enamel defects salivary dysfunction and poor oral hygiene could be predisposing factors to extrinsic discoloration Small pits and defects on the outer surface of the enamel can lead to an accumulation of food particles and stains from beverages tobacco and other topical agents on its surface causing the discoloration Salivary dysfunction such as decreased salivation can lead to difficulties in removing food debris from the tooth surface and can thus contribute to the staining of teeth Conditions that are associated with a reduction in the salivation are salivary gland obstruction and infection Sjögren syndrome head and neck radiation therapy for cancer chemotherapy and multiple medications eg anticholinergics antihypertensive antipsychotics and antihistamines All of these can cause teeth discoloration Patel et al 2013

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None