Ignite Creation Date:
2024-10-25 @ 8:01 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06554041
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-05
Brief Title:
Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to learn how different materials used in dental implants affect the surrounding gum tissue in adults who need dental implants The main questions it aims to answer are
How do different materials titanium PEEK zirconia and lithium disilicate affect inflammation around dental implants What changes occur in inflammation markers in the gum tissue after 3 and 6 months Researchers will compare the different materials to see which one causes the least amount of inflammation
Participants will
Receive dental implants made from different materials Have samples of fluid from around their implants collected for analysis at 3 and 6 months
Undergo regular dental check-ups to measure gum health such as bleeding and pocket depth around the implants
How do different materials titanium PEEK zirconia and lithium disilicate affect inflammation around dental implants What changes occur in inflammation markers in the gum tissue after 3 and 6 months Researchers will compare the different materials to see which one causes the least amount of inflammation
Participants will
Receive dental implants made from different materials Have samples of fluid from around their implants collected for analysis at 3 and 6 months
Undergo regular dental check-ups to measure gum health such as bleeding and pocket depth around the implants
Detailed Description:
The study will involve a total of 40 edentulous patients each missing four teeth in the posterior region of the mandible or maxillae Each patient will receive four dental implants and single crowns made from different materials The primary objectives are to evaluate biomarkers in peri-implant crevicular fluid and to assess the changes in these biomarkers after three and six months of loading This research will help determine the biocompatibility of the materials and their potential to cause peri-implantitis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None