Viewing Study NCT06573918



Ignite Creation Date: 2024-10-25 @ 8:01 PM
Last Modification Date: 2024-10-26 @ 3:38 PM
Study NCT ID: NCT06573918
Status: COMPLETED
Last Update Posted: None
First Post: 2024-08-23

Brief Title: EMG-Assessed Paratonia A New Approach to Response Inhibition
Sponsor: None
Organization: None

Study Overview

Official Title: EMG-Assessed Paratonia A Novel Approach to Investigating Motor Response Inhibition in Healthy Subjects
Status: COMPLETED
Status Verified Date: 2024-08
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Paratonia is the inability to relax muscles during the assessment of muscle tone in the absence of spasticity and parkinsonian rigidity It can be evaluated qualitatively using clinical scales and objectively through surface electromyography EMG-assessed paratonia It is widely accepted that paratonia represents a manifestation of impaired motor response inhibition due to frontal lobe dysfunction

Traditionally motor response inhibition has been assessed using experimental protocols such as gono-go and stop-signal tasks Research has shown that athletes particularly those engaged in open-skill sports demonstrate superior motor response inhibition compared to sedentary individuals Even amateur athletes exhibit better motor response inhibition than sedentary individuals though to a lesser extent than professional athletes

Given that the etiology of paratonia involves a defect in motor response inhibition it is hypothesized that EMG-assessed paratonia could become a novel approach for evaluating motor response inhibition The present study was designed to validate this hypothesis Specifically we first tested whether EMG-assessed paratonia in healthy subjects can reveal a well-known aspect of motor response inhibition namely its correlation with the level of physical activity
Detailed Description: EMG-assessed paratonia was analyzed and compared to assess motor response efficiency in three groups of healthy young adults with different levels of physical activity professional athletes engaged in closed and open skills sports amateurs and sedentary individuals To analyze EMG-assessed paratonia two surface electrodes were attached to the biceps and triceps brachii muscles during passive flexion-extension movements of the elbow while the participant remained in a state of maximum relaxation Any EMG activity detected during these movements was attributed to an inability to relax thereby reflecting their degree of paratonia

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None