Ignite Creation Date:
2024-10-25 @ 8:04 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06645756
Status:
RECRUITING
Last Update Posted:
None
First Post:
2023-09-21
Brief Title:
Comparative Analysis of Postprandial Effects in Healthy and Obese Individuals
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparative Analysis of Postprandial Effects in Healthy and Obese Individuals
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CAPE
Brief Summary:
After eating blood composition changes including increased triglycerides and glucose which can trigger postprandial inflammation Particularly with high-fat foods pro-inflammatory lipopolysaccharide LPS increases This activates leukocytes to release pro-inflammatory cytokines In industrialized countries where snacking is common many people spend the day in a postprandial state Obese individuals tend to have chronic inflammation and show increased susceptibility to infections such as SARS-CoV-2 The main objective of the study is to investigate the response of leukocytes and the serum metabolome after food intake in individuals with obesity compared to healthy individuals focusing on LPS as a key stimulus of innate immunity
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None