Ignite Creation Date:
2024-10-25 @ 8:05 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06531785
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-29
Brief Title:
Role of Lung Ultrasound in Screening for Interstitial Lung Disease in Patients With Rheumatoid Arthritis
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Role of Lung Ultrasound in Screening for Interstitial Lung Disease in Patients With Rheumatoid Arthritis
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this observational cross-sectional study is to assess accuracy of Lung Ultrasound to early diagnose ILD among Rheumatoid arthritis patients Rheumatoid arthritis patients with suggestive history of chest troubles will be evaluated using chest ultrasound and high resolution CT chest to evaluate ability of chest ultrasound to early diagnose ILD among rheumatoid arthritis patients
Detailed Description:
Interstitial lung disease ILD is a common complication of connective tissue disease CTD and a leading cause of morbidity and mortality Thus early diagnosis and treatment may improve the prognosis of patients with ILD
High-resolution computed tomography HRCT is the gold standard for ILD diagnosis It can detect the location and type of lesions through its high resolution Unfortunately it is hampered by high cost and potential risks associated with radiation exposure especially for pregnant women
Accordingly finding a low-cost non-invasive and non-ionizing diagnostic method is necessary for ILD Lung ultrasound LUS has all of these advantages and is an accessible bedside procedure As a result it is easily accepted by patients Over the last 20 years LUS has mainly been applied in CTD-ILD diagnosis where it has shown high sensitivity and specificity The assessment of ILD by LUS is determined by the number of B-lines which appear as a comet tail signal and originate from the pleural line without fading to the edge of the screen
The total number of B-lines was found to correlate well with the HRCT score To assess the number of B-lines previous studies used various scoring systems by designing different intercostal spaces LIS such as 72 LIS 50 LIS and 14 LIS This study aims to assess Lung ultrasound as a screening tool for early interstitial lung disease in connective tissue disease patients
High-resolution computed tomography HRCT is the gold standard for ILD diagnosis It can detect the location and type of lesions through its high resolution Unfortunately it is hampered by high cost and potential risks associated with radiation exposure especially for pregnant women
Accordingly finding a low-cost non-invasive and non-ionizing diagnostic method is necessary for ILD Lung ultrasound LUS has all of these advantages and is an accessible bedside procedure As a result it is easily accepted by patients Over the last 20 years LUS has mainly been applied in CTD-ILD diagnosis where it has shown high sensitivity and specificity The assessment of ILD by LUS is determined by the number of B-lines which appear as a comet tail signal and originate from the pleural line without fading to the edge of the screen
The total number of B-lines was found to correlate well with the HRCT score To assess the number of B-lines previous studies used various scoring systems by designing different intercostal spaces LIS such as 72 LIS 50 LIS and 14 LIS This study aims to assess Lung ultrasound as a screening tool for early interstitial lung disease in connective tissue disease patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None