Ignite Creation Date:
2024-10-25 @ 8:06 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06555978
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
None
First Post:
2024-08-08
Brief Title:
Ageing BIOmarker Study in Singaporeans
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Ageing BIOmarker Study in Singaporeans ABIOS
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ABIOS
Brief Summary:
The Ageing BIOmarker Study in Singaporeans ABIOS aims to understand the biological aging processes and how they affect health among people in Singapore As people grow older their risk of developing chronic diseases increases This study aims to better understand the biological changes that come with age particularly in three major ethnic groups Chinese Malay and Indian adults over 21 years old By examining a range of health indicators such as DNA methylation inflammation metabolism cardiovascular health physical function and physical activity ie molecular physiological and digital biomarkers of ageing the study seeks to identify how ethnicity lifestyle and socioeconomic factors influence ageing This unique study focuses on an all-Asian population aiming to enhance our understanding of healthy aging across different ethnic groups
Detailed Description:
Biological ageing is the primary driver of age-associated chronic diseases in older adults Asian populations have been underrepresented in studies developing biological age predictors and understanding age-related diseases Thus the Ageing BIOmarker Study in Singaporeans ABIOS aims to characterise the biomarkers of ageing in Singaporeans exploring associations between molecular physiological and digital biomarkers of ageing
This is a single-centre cross-sectional study that recruits healthy community-dwelling adults 21 years from three different ethnic groups Chinese Malay and Indian Molecular biomarkers of ageing include a multi-omics approach such as DNA methylation and metabolic and inflammatory parameters in blood saliva and stool Physiological biomarkers of ageing include bone density body composition skin autofluorescence arterial stiffness physical performance eg muscle strength and flexibility cognition and nutritional status Digital biomarkers of ageing include three-dimensional facial morphology and objective physical activity Additional factors such as habitual physical activity dietary patterns and medical history are also examined The associations between the molecular physiological and digital phenotypes will be explored
By examining diverse age-related biomarkers clinical indicators and lifestyle factors ABIOS will offer unique insights into the ageing process within these ethnic groups to develop health policies and interventions for promoting healthy ageing in an all-Asian population
This is a single-centre cross-sectional study that recruits healthy community-dwelling adults 21 years from three different ethnic groups Chinese Malay and Indian Molecular biomarkers of ageing include a multi-omics approach such as DNA methylation and metabolic and inflammatory parameters in blood saliva and stool Physiological biomarkers of ageing include bone density body composition skin autofluorescence arterial stiffness physical performance eg muscle strength and flexibility cognition and nutritional status Digital biomarkers of ageing include three-dimensional facial morphology and objective physical activity Additional factors such as habitual physical activity dietary patterns and medical history are also examined The associations between the molecular physiological and digital phenotypes will be explored
By examining diverse age-related biomarkers clinical indicators and lifestyle factors ABIOS will offer unique insights into the ageing process within these ethnic groups to develop health policies and interventions for promoting healthy ageing in an all-Asian population
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None