Viewing Study NCT06502496



Ignite Creation Date: 2024-10-26 @ 3:34 PM
Last Modification Date: 2024-10-26 @ 3:34 PM
Study NCT ID: NCT06502496
Status: NOT_YET_RECRUITING
Last Update Posted: None
First Post: 2024-07-09

Brief Title: Behavioural Study in Chronic Pain Creativity and Motivation and Circuits Involved in Functional MRI
Sponsor: None
Organization: None

Study Overview

Official Title: Behavioural Study in Chronic Pain Creativity and Motivation and Circuits Involved in Functional MRI
Status: NOT_YET_RECRUITING
Status Verified Date: 2024-07
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: AART
Brief Summary: Being creative means having the ability to produce ideas actions or works that are original and different from what we have already done This process involves mental flexibility in particular the association of distant ideas or divergent thinking This creative potential is complex and depends on a number of factors both internal personality motivation emotional state stress and external to the individual socio-cultural context The generation of creative ideas involves the fronto-striatal circuit with a balance between flexibility and perseverance The striatum is central to the reward system and mental flexibility while the prefrontal cortex is involved in executive control underpinning perseverance functions Dopamine plays a key role in this balance and changes in dopamine levels depending on the type of receptor activated will have a direct impact on the transition between mental flexibility and perseverance Furthermore in the context of chronic pain changes in connectivity and activity can be observed in neuroimaging in these same regions of the reward circuit This suggests that the dopaminergic system is also involved in the chronicisation of pain The creative process would therefore be correlated with the dopaminergic reward system involving several dimensions both cognitive in terms of mental flexibility coping strategies and perseverance and motivational In this context art therapy treatments are beginning to be studied particularly in patients suffering from Alzheimers or Parkinsons disease showing improvements in anxiety and depression

Art therapy has not yet been widely proposed or studied for patients suffering from chronic pain A more detailed behavioural study would confirm and clarify the clinical benefits for patients by exploring the neuronal circuits involved particularly the dopaminergic reward system
Detailed Description: None

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None