Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06503523
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-07-10
Brief Title:
The Effects of Performing a Motor Imagery Task on Cortical Excitability During Acute Experimental Muscle Pain and Acute Itch
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Investigation of the Neurophysiological and Psychological Aspects of Itch
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this project is to determine the effects of performing a motor imagery task on cortical excitability during acute experimental muscle pain induced by hypertonic saline acute histaminergic itch induced by histamine and non-histaminergic itch stimulation triggered by Cowhage We hypothesize that motor imagery will counteract the alterations in cortical excitability observed during experimental muscle pain and both itch models
Detailed Description:
Itch and pain share many similarities and dissimilarities in terms of the mechanisms and molecules involved Many studies have been conducted to explain all the neurophysiological aspects involved in the pain process and cortical adaptations have been provoked in healthy individuals using experimental pain models Unfortunately all these aspects still need to be clarified regarding itch Has been previously demonstrated that motor imagery can counteracted the pain-induced decrease in corticospinal excitability observed during acute pain and it has also been proposed as a potential intervention for individuals with pain to restore maladaptive neuroplasticity However whether motor imagery can similarly counteract the itch-induced cortical changes remains unclear Therefore the aim of this project is to investigate whether motor imagery would counteract the reduction in cortical excitability during acute itch similar to the effects observed in the context of acute pain
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None