Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06507306
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-01
Brief Title:
A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
Sponsor:
None
Organization:
None
Study Overview
Official Title:
A Phase 11b Open-label Multicenter Dose Escalation and Dose Expansion Study Evaluating the Safety Tolerability Pharmacokinetics and Efficacy of KQB198 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to learn if KQB198 works to treat advanced solid tumor cancer in adults It will also learn about the safety of KQB198 The main questions it aims to answer are
What is the safe dose of KQB198 by itself or in combination with other anti-cancer drugs
Does KQB198 alone or in combination with other anti-cancer drugs decrease the size of the tumor
What happens to KQB198 in the body
Participants will
Take KQB198 daily alone or in combination with another anti-cancer drug
Visit the clinic about 8 times in the first 8 weeks and then once every 4 weeks after that
What is the safe dose of KQB198 by itself or in combination with other anti-cancer drugs
Does KQB198 alone or in combination with other anti-cancer drugs decrease the size of the tumor
What happens to KQB198 in the body
Participants will
Take KQB198 daily alone or in combination with another anti-cancer drug
Visit the clinic about 8 times in the first 8 weeks and then once every 4 weeks after that
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None