Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06507410
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-11
Brief Title:
Additive Effects of Clonidine Used in Propofol Sedation in Colonoscopy
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Additive Effects of Clonidine Used in Propofol Sedation in Colonoscopy
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The objective of this study was to compare safety satisfaction and efficiency outcomes of propofol versus propofol with clonidine in patients undergoing colonoscopy
Detailed Description:
Colonoscopy is one of the most common procedures in the world Colonoscopy is a procedure often performed for prevention diagnosis and treatment of a variety of symptoms and diseases of the lower digestive tract and sedation or anesthesia should be considered as an important tool to increase its effectiveness
Sedation and analgesia are considered key components as they reduce anxiety and discomfort and therefore improve the procedure tolerability and patient satisfaction minimize risk of complications and provide better conditions for the examination
Propofol may be used alone or in combination with opioids andor benzodiazepines
The use of propofol alone requires higher doses which may lead to increased incidence of side effects However the risks and benefits of adding analgesic and sedative to propofol are controversial and the selection of drugs is a crucial factor in determining the outcomes
Clonidine apparently produces its sedative and anaesthetic-sparing effects by stimulation of centrally located alpha2 adrenoceptors Analgesia seems to be mediated mainly by activation of alpha2 adrenoceptors in the dorsal horn of the spinal cord
Sedation and analgesia are considered key components as they reduce anxiety and discomfort and therefore improve the procedure tolerability and patient satisfaction minimize risk of complications and provide better conditions for the examination
Propofol may be used alone or in combination with opioids andor benzodiazepines
The use of propofol alone requires higher doses which may lead to increased incidence of side effects However the risks and benefits of adding analgesic and sedative to propofol are controversial and the selection of drugs is a crucial factor in determining the outcomes
Clonidine apparently produces its sedative and anaesthetic-sparing effects by stimulation of centrally located alpha2 adrenoceptors Analgesia seems to be mediated mainly by activation of alpha2 adrenoceptors in the dorsal horn of the spinal cord
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None