Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06511661
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
None
First Post:
2024-07-15
Brief Title:
Prognostic Significance of the Uncertain Resection in NSCLC
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Prognostic Significance of the Uncertain Resection Based on the Extent of Nodal Dissection for Non-small Cell Lung Cancer A Propensity Score Matching Retrospective Study
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The concept of residual tumor classification proposed by the Union for International Cancer Control UICC was used to assess the completeness of surgical resection and non-small cell lung cancer NSCLC patients with incomplete resection were more likely to occur recurrence leading to significantly poor survival But this R classification only refers to the surgical margin and neglects other factors associated with surgical quality such as the extent of lymph node dissection LND Therefore the International Association for the Study of Lung Cancer IASLC proposed the definition of uncertain resection Run which includes the suboptimal extent of LND However the clinical significance of Run is still controversial On the one hand some researches demonstrated that Run had definite prognostic significance with Run survival stratifying between R0 and R1 On the other hand some studies indicated that in early-stage NSCLC the suboptimal extent of LND had no impact on survival and the concept of Run might be insignificant in these patients Even in those studies supporting the prognostic significance of Run which kind of patients is suitable for Run was still unclear Thus the investigators explore the impact of the Run on the long-term survival of patients with NSCLC using a large cohort in China to identify those patients who could really benefit from the LND required by the R0 classification proposed by IASLC
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None