Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06514170
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-09
Brief Title:
Gastrointestinal Dysfunction in Aortic Surgery Patients
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Assessment of Gastrointestinal Dysfunction Through GIDS Scale and Intestinal Damage Biomarkers in Critically Ill Patients Undergoing Aortic Surgery and Its Association With Clinical Outcomes
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to determine the association of gastrointestinal dysfunction through the Gastrointestinal Dysfunction Scale GIDS tool and serum concentrations of citrulline and Intestinal fatty-acid binding protein I-FABP with primary calories received protein received parenteral nutrition requirement and 28-day mortality in the intensive care unit ICU and secondary development of pneumonia surgical and cardiovascular complications in the ICU length of hospital and ICU stay duration of mechanical ventilation clinical outcomes in critically ill patients undergoing aortic surgery
Detailed Description:
The treatment of choice for various cardiovascular diseases often involves cardiac surgery including aortic surgery which is performed to correct conditions related to this major vessel such as aneurysms stenosis aortic dissections as well as issues affecting the aortic valve With the increasing prevalence of non-communicable chronic diseases a 46 increase in demand for cardiac surgeries is projected by 2025 The post-surgical period commonly in the intensive care unit ICU increases the risk of complications especially in patients with pre-existing risk factors In this regard gastrointestinal GI dysfunction affects up to 63 of patients being associated with complications and a mortality rate of 55 to 60 Early detection of GI dysfunction allows for the implementation of management strategies Additionally the administration of appropriate nutritional therapy is essential for recovery and GI dysfunction may limit nutrient absorption Inadequate caloric intake has been linked to increased morbidity and mortality Tools such as GIDS Gastrointestinal Dysfunction Scale and biomarkers like citrulline and I-FABP enable early evaluation of GI function advancing monitoring and management Identifying changes before serious complications arise allows for early and personalized interventions Early detection not only prevents complications and improves quality of life but may also reduce mortality This research project aims to address these gaps by early assessing GI dysfunction in post-aortic surgery patients Utilizing the GIDS tool and biomarkers such as citrulline and I-FABP the goal is to identify GI dysfunction early and its impact on nutrition administration
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None