Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06514924
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-07-09
Brief Title:
Secular Change of Height in Turkish Young Adults
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Young Turkish Adults Show a Continuing Positive Secular Change of Height But a Worrying Increase of Overweight in Males
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Current Turkish growth reference charts based on anthropometric measurements of individuals with high socioeconomic status in Istanbul in 1989-2002 TK2002 had shown an increase of mean adult height 14 and 27 cm in males and females compared with 1978 Given recent improvements in nutrition hygiene and access to preventive health services it is hypothesized that this positive secular trend may continue A prior power analysis 95 power showed that at least 122 subjects of each sex were needed to detect a 18 cm height increase p005 vs TK2002 In 2023-2024 a sample of Turkish young adults 18-26 years was randomly selected from 65000 students at Istanbul University originating from every region of Turkey TK2024 Height weight and socioeconomic status SES categorized into four groups were recorded and body mass index BMI was calculated Adult height and BMI were compared with TK2002 and with young adults of Turkish origin living in the Netherlands measured in 2009 NL2009
Detailed Description:
Study setting A sample of students was randomly selected from 65000 students at Istanbul University originating from every region of Turkey in 2023-2024 TK2024 The inclusion criteria for the study were I age between 18 and 26 years II being a student at Istanbul University and III volunteering to participate in the study The exclusion criteria were I diagnosis of a chronic disease II a history of surgery that can affect linear growth III diagnosis of growth retardation IV a history of growth hormone administration V having a parent born outside of Turkey VI birth height or weight less than -2 SDS and VII current height or BMI less than -3 SDS or greater than 3 SDS This study was approved by the Local Ethical Committee of Istanbul Faculty of Medicine and funded by the Scientific Research Projects Coordination Unit of Istanbul University Voluntary informed written consent was obtained from all the participants The students medical history birthplace high school graduation province parental education level and occupation and household income were recorded through a questionnaire
Measurements Standing height was measured with bare feet using a portable stadiometer and documented to the nearest 01 cm Weight was determined in light clothing using a digital scale and recorded to the closest 01 kg Two trained technicians performed all measurements Height measurements were repeated twice and the mean value was calculated If the difference exceeded 03 cm a third measurement was taken and the average of the two closest values was used Body mass index BMI was calculated as weight kg divided by height m square
Classification of socioeconomic status After collecting all the data the participants were classified into four groups according to socioeconomic status SES SES-1 to 4 SES was determined based on the criteria used in previous national growth studies which were modified to better align with current conditions This classification is determined by the educational level of both parents and the fathers occupation Meeting all three criteria was necessary for inclusion in the upper levels of the SES If any of these criteria are not met individuals were assigned to a lower SES level
In the present study the SES assessment questionnaire is derived from the TK2002 questionnaire with a single modification the educational level of parents has been increased by one level This update is based on data from the Turkish Statistical Institute which reported a 26 average increase in the duration of education in Turkey between 2008 and 2022
Comparative Analyses To demonstrate the secular trend a comparison was made between the data from the present study and the data from the 18-year-old age group in the TK2002 study which served as the basis for the current national growth curves The data for 18-year-olds in TK2002 were collected from measurements of senior high school students in six affluent districts of Istanbul In line with the methodology of the present study TK2002 also categorized participants into four SES groups based on an SES questionnaire
The technical specifications and measurement methods of the instruments used in this study are identical to those used in TK2002 ensuring comparability and consistency across both studies
Adult height and BMI were also compared with TK2002 and with young adults of Turkish origin living in the Netherlands measured in 2009 NL2009 Age SES and geographical region were used to conduct subgroup analyses Age groups were divided into 18-22 and 23-26 years Separate subgroups were formed for the seven regions of Turkey based on birthplace or high school graduation
Measurements Standing height was measured with bare feet using a portable stadiometer and documented to the nearest 01 cm Weight was determined in light clothing using a digital scale and recorded to the closest 01 kg Two trained technicians performed all measurements Height measurements were repeated twice and the mean value was calculated If the difference exceeded 03 cm a third measurement was taken and the average of the two closest values was used Body mass index BMI was calculated as weight kg divided by height m square
Classification of socioeconomic status After collecting all the data the participants were classified into four groups according to socioeconomic status SES SES-1 to 4 SES was determined based on the criteria used in previous national growth studies which were modified to better align with current conditions This classification is determined by the educational level of both parents and the fathers occupation Meeting all three criteria was necessary for inclusion in the upper levels of the SES If any of these criteria are not met individuals were assigned to a lower SES level
In the present study the SES assessment questionnaire is derived from the TK2002 questionnaire with a single modification the educational level of parents has been increased by one level This update is based on data from the Turkish Statistical Institute which reported a 26 average increase in the duration of education in Turkey between 2008 and 2022
Comparative Analyses To demonstrate the secular trend a comparison was made between the data from the present study and the data from the 18-year-old age group in the TK2002 study which served as the basis for the current national growth curves The data for 18-year-olds in TK2002 were collected from measurements of senior high school students in six affluent districts of Istanbul In line with the methodology of the present study TK2002 also categorized participants into four SES groups based on an SES questionnaire
The technical specifications and measurement methods of the instruments used in this study are identical to those used in TK2002 ensuring comparability and consistency across both studies
Adult height and BMI were also compared with TK2002 and with young adults of Turkish origin living in the Netherlands measured in 2009 NL2009 Age SES and geographical region were used to conduct subgroup analyses Age groups were divided into 18-22 and 23-26 years Separate subgroups were formed for the seven regions of Turkey based on birthplace or high school graduation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None