Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06519162
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-11
Brief Title:
Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Exploration of Liver-gut Axis Through Identification of Liver Disease-specific Microbiome
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
LGAS
Brief Summary:
In this study we aim to identify gut microbiomes specific to patients with chronic refractory liver disease and to conduct a gut-liver axis study on the pathogenesis and disease progression
Detailed Description:
1 The investigators will recruit study participants aged 19 and older who have been diagnosed with autoimmune hepatitis primary biliary cholangitis primary sclerosing cholangitis non-alcoholic steatohepatitis or liver abscess along with their household members and who have agreed to participate in this study at Chungnam National University Hospital
2 The investigators collect and analyze blood and stool samples from the patients and their household members
3 Sampling Method Non-Probability Samples
4 Study Population
Group of autoimmune hepatitis patients with definite autoimmune hepatitis or their healthy households for controls Group of primary biliary cholangitis patients with definite primary biliary cholangitis or their healthy households for controls Group of primary sclerosing cholangitis patients with definite primary sclerosing cholangitis or their healthy households for controls Group of non-alcoholic steatohepatitis patients with definite non-alcoholic steatohepatitis or their healthy households for controls Group of liver abscess patients with definite liver abscess or their healthy households for controls
2 The investigators collect and analyze blood and stool samples from the patients and their household members
3 Sampling Method Non-Probability Samples
4 Study Population
Group of autoimmune hepatitis patients with definite autoimmune hepatitis or their healthy households for controls Group of primary biliary cholangitis patients with definite primary biliary cholangitis or their healthy households for controls Group of primary sclerosing cholangitis patients with definite primary sclerosing cholangitis or their healthy households for controls Group of non-alcoholic steatohepatitis patients with definite non-alcoholic steatohepatitis or their healthy households for controls Group of liver abscess patients with definite liver abscess or their healthy households for controls
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None